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2:21:49ENFocused Protection, Not Lockdowns: Jay Bhattacharya on What Public Health Got WrongGuest Jay Bhattacharya · Host Lex FridmanThe Stanford physician and co-author of the Great Barrington Declaration tells Lex Fridman why age-stratified risk, seroprevalence data, and the ignored costs of isolation pointed to a different COVID strategy.
2:15:56ENA Theory That Fits Anything Is Not Even WrongGuest Peter Woit · Host Lex FridmanColumbia physicist Peter Woit tells Lex Fridman why string theory's original idea emptied out, why four dimensions are enough, and what twistor theory still offers.
3:38:43ENConsciousness Is a Step Down From IntelligenceGuest Stephen Wolfram · Host Lex FridmanStephen Wolfram tells Lex Fridman how simple programs, a discrete fabric of space, and a computationally bounded observer together explain complexity, physics, and why the universe exists.
2:56:42ENSilicon Does Not Emit LightGuest Jeffrey Shainline · Host Lex FridmanNIST physicist Jeffrey Shainline on why a brain-like computer should calculate in superconducting electronics and talk with single photons.
1:52:17ENOld Theories Rarely Die of Contradiction. They Stop Making New Things.Guest Jed Buchwald · Host Lex FridmanCaltech historian Jed Buchwald talks with Lex Fridman about Kuhn, Newton, and why scientific change is a victory of productivity more than of proof.
2:54:52ENThe Marvelous Proof Still Lives in the MarginHost Lex FridmanLuís and João Batalha, the brothers behind Fermat's Library, talk with Lex Fridman about hidden backstories, a publishing system that buys its own work twice, and how to sit with a paper until it finally clicks.
2:13:21ENThe Fourth Deduction Often Turns Out to Be the First PrincipleGuest Cumrun Vafa · Host Lex FridmanHarvard string theorist Cumrun Vafa on why physicists distrust deduction, how a graviton fell out of a formula nobody wrote for gravity, and what extra dimensions are actually for.
2:39:53ENThere's Something at the Edge of the Solar SystemGuest Konstantin Batygin · Host Lex FridmanCaltech planetary astrophysicist Konstantin Batygin tells Lex Fridman how a hypothesized five-Earth-mass world shepherds the distant Kuiper Belt — and why a photograph would end the argument.
1:59:28ENSara Walker says “what is life?” is the wrong questionGuest Sara Walker · Host Lex FridmanThe astrobiologist and theoretical physicist tells Lex Fridman that origin-of-life science is stuck on molecules, and that causation, assembly, and planetary-scale information are closer to the real problem.
1:58:12ENThe Universe Doesn't Sacrifice. That's Why Phosphine Might Mean Life.Guest Clara Sousa-Silva · Host Lex FridmanQuantum astrochemist Clara Sousa-Silva on the contested Venus detection, a molecule nobody could spell, and why she treats cosmic meaninglessness as a relief.
3:17:09ENWhat Science Is Left When Institutions Decide What Cannot Be SaidGuest Bret Weinstein · Host Lex FridmanEvolutionary biologist Bret Weinstein talks with Lex Fridman about lab-leak evidence, ivermectin, captured public-health agencies, and why the 1% at the fringe is the key to progress.
2:41:47ENGeometry Is the Cilantro of MathGuest Jordan Ellenberg · Host Lex FridmanJordan Ellenberg tells Lex Fridman that the last 150 years of mathematics have been about one question: when two things count as the same.
2:22:20ENThe closer quarks get, the weaker they pullGuest Frank Wilczek · Host Lex FridmanNobel physicist Frank Wilczek talks with Lex Fridman about asymptotic freedom, beauty, dark matter, consciousness, and whether a theory of everything would even help.
1:56:54ENKatherine de Kleer still calls moons planetsGuest Katherine de Kleer · Host Lex FridmanThe Caltech planetary scientist talks with Lex Fridman about Pluto’s demotion, tidal heating on Io, hidden oceans, and the ice that may explain Oumuamua.
2:51:17ENOumuamua Wasn't Supposed to Exist. Avi Loeb Wants a Photograph Next Time.Guest Avi Loeb · Host Lex FridmanHarvard astrophysicist Avi Loeb tells Lex Fridman why the first interstellar visitor looks more like a lightsail than a rock — and why that question is still treated as unscientific.
4:23:39ENThe Universe's Rule Might Fit on a PostcardGuest Stephen Wolfram · Host Lex FridmanStephen Wolfram tells Lex Fridman how a short computational rule on a hypergraph could generate space, time, relativity, and quantum mechanics.
2:01:15ENNobody Died from the Fukushima ReactorsGuest Ian Hutchinson · Host Lex FridmanMIT plasma physicist Ian Hutchinson on fusion, a hundredfold carbon cut, scientism, and why faith is more than believing unproven claims.
1:38:20ENParticle physics is badly named: Harry Cliff on fields, the Higgs, and a collider with no bossGuest Harry Cliff · Host Lex FridmanA Cambridge physicist walks Lex Fridman through the Large Hadron Collider, the Standard Model, and why the vacuum is not empty.
3:11:09ENIn the computational universe, the animals are always smarter than youGuest Stephen Wolfram · Host Lex FridmanStephen Wolfram talks with Lex Fridman about Rule 30, computational irreducibility, a hypergraph model of physics, and why Wolfram Language is a notation for talking about the world.
2:46:36ENThe Great Nap Is OverGuest Eric Weinstein · Host Lex FridmanMathematician Eric Weinstein tells Lex Fridman that seventy-five quiet years selected the wrong leaders, then walks through Geometric Unity, the theory he kept in a drawer for decades.
11:26ENRichard Dawkins on Memes, the Internet and Why Wrong Ideas SpreadGuest Richard Dawkins · Host Lex FridmanThe man who coined the word explains to Lex Fridman what makes a meme more than a metaphor, why the internet is a step change for ideas, and why an idea, like a peacock's tail, doesn't need to be true or useful to spread.
1:09:52ENLee Smolin Does Not Believe in the Scientific MethodGuest Lee Smolin · Host Lex FridmanThe theoretical physicist talks with Lex Fridman about realism, the measurement problem, and why finishing Einstein’s revolution means treating time as fundamental and locality as optional.
1:09:12ENAnn Druyan on Voyager, Carl Sagan, and Love Without IllusionGuest Ann Druyan · Host Lex FridmanThe creative director of the Voyager Golden Record argues that science is an error-correcting way of seeing the universe — and of seeing another person.
1:02:45ENAliens Would Count. They Probably Wouldn't Write e^x.Guest Grant Sanderson · Host Lex FridmanGrant Sanderson of 3Blue1Brown talks with Lex Fridman about notation, infinity, and why a visualization has to pick a single arrow.
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