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2:58:38ENSleep runs on two clocks — and worrying about it can be worse than a short nightGuest Andrew Huberman · Host Lex FridmanStanford neuroscientist Andrew Huberman tells Lex Fridman how adenosine and body temperature decide when you crash, why dreams work like overnight therapy, and what the chemistry of effort has to do with not quitting.
2:44:19ENSpeech Was a Bundle, and the Internet Unbundled ItGuest Eric Weinstein · Host Lex FridmanOn his fourth Lex Fridman Podcast appearance, Eric Weinstein talks through digital speech, reputation as a control tool, gauge-theoretic economics, and the unfinished physics he calls geometric unity.
2:39:15ENCraftsmanship, Graphs and Consciousness: Jim Keller on Building Computers That ThinkGuest Jim Keller · Host Lex FridmanLegendary chip architect Jim Keller talks with Lex Fridman about design philosophy, the future of AI hardware, the human mind and how to live well.
2:16:07ENAsk What Could Go Right: Jason Calacanis on Robinhood, Loyalty, and Two Checks for TeslaGuest Jason Calacanis · Host Lex FridmanThe angel investor and All-In co-host walks Lex Fridman from a Palo Alto dive bar to GameStop, Silicon Valley’s war on friction, and a friendship that kept a car company alive for twelve extra days.
3:03:38ENA Ten-Day Language That Still Runs the WebGuest Brendan Eich · Host Lex FridmanBrendan Eich tells Lex Fridman how JavaScript, Firefox, Mozilla, and Brave were built from rushed bets, open-source escape pods, and accidental tracking.
1:49:56ENA 21-Year-Old at a Party Called GameStop. He Was Right.Guest Richard Craib · Host Lex FridmanNumerai founder Richard Craib talks with Lex Fridman about WallStreetBets, crowdsourced machine learning, and why finance is a machine for pulling the future into the present.
1:44:32ENThe Philosopher’s Risk: Zev Weinstein on Stagnation, Truth, and the Courage to Change Your MindGuest Zev Weinstein · Host Lex FridmanZev Weinstein talks with Lex Fridman about why radical thought is both dangerous and necessary, and how truth, language, media, mathematics and mortality shape a meaningful life.
1:39:29ENElectric engines, 20-nanometer cones, and why Natalya Bailey would skip the first thousand on MarsGuest Natalya Bailey · Host Lex FridmanThe Accion Systems founder walks Lex Fridman from ion physics to orbital debris, chip-made thrusters, and the kind of culture that oozes out of a founder.
2:28:38ENLeave Them the Debt: Tim Dillon on Comedy, Censorship, and a Country That Feels ScrewedGuest Tim Dillon · Host Lex FridmanComedian Tim Dillon talks with Lex Fridman about unpaid graves, bad life advice, algorithmic gatekeepers, Alex Jones, and why so many people feel powerless.
1:18:35ENAn AI That Walks Among Us May Have to Know DepressionHost Lex FridmanIn a January 2021 AMA, Lex Fridman answers listeners on suffering machines, immigration, aliens, career pivots, and why happiness is a signal rather than a goal.
3:02:43ENHumanity Cannot Survive on the Right Person Showing Up at the Right TimeGuest Max Tegmark · Host Lex FridmanMIT physicist Max Tegmark tells Lex Fridman why AI should be as well understood as rockets, why 2020 was a warning on weapons and news, and why luck is a terrible long-term plan.
2:51:17ENOumuamua Wasn't Supposed to Exist. Avi Loeb Wants a Photograph Next Time.Guest Avi Loeb · Host Lex FridmanHarvard astrophysicist Avi Loeb tells Lex Fridman why the first interstellar visitor looks more like a lightsail than a rock — and why that question is still treated as unscientific.
2:17:42ENThe building block of life is a bead on a string, not the whole proteinGuest Dmitry Korkin · Host Lex FridmanDmitry Korkin tells Lex Fridman why protein domains, a triangular spike, and a conservative viral shell matter more than the AlphaFold headline, and why a Nobel laureate once answered a midnight forum post.
1:37:46ENAll-In Debates Trump’s Platform Bans and Online Free ExpressionHost Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergDays after the January 6 attack, the hosts disagree about platform power, public safety and how political opponents can reconcile.
1:16:12ENDan Gable Won the Olympics 57–0. He Still Talks About the Match He LostGuest Dan Gable · Host Lex FridmanThe Iowa wrestling legend on Russian technique, American toughness, the murder of his sister, and why he took the word choice out of his life.
1:28:46ENThe Speech Company That Gets Paid to Label Its Own Training DataGuest Dan Kokotov · Host Lex FridmanRev VP of engineering Dan Kokotov tells Lex Fridman why a $1.25-a-minute human transcript, a 14% machine word-error rate, and a two-sided freelancer market are the same flywheel.
3:08:23ENTake One Red Pill, Not the Whole BottleGuest Michael Malice · Host Lex FridmanMichael Malice talks with Lex Fridman about humor as a filter, the White Pill, anarchism, and how to want happiness without swallowing cynicism.
3:01:27ENA Belief Does Not Have to Be True to Remake the WorldGuest Diana Walsh Pasulka · Host Lex FridmanReligious-studies scholar Diana Walsh Pasulka tells Lex Fridman how Catholic limbo, Nietzsche, Silicon Valley “downloads,” and a desert monolith all describe the same machinery of belief and technology.
2:02:45ENSteal the Code: You Get Zero Points for Making the Algorithm RunHost Lex FridmanCharles Isbell and Michael Littman tell Lex Fridman why machine learning is not just statistics, why struggle has to stay hopeful, and what a $6,600 online master's actually sells.
2:23:10ENBuilding a Driver, Not a Copilot: Waymo CTO Dmitri Dolgov on Fully Driverless CarsGuest Dmitri Dolgov · Host Lex FridmanFrom a 3 a.m. parking-lot planner at Stanford to a public robotaxi in Phoenix, Dolgov tells Lex Fridman why driver assist and a real driver are different products.
2:18:26ENThe Dollar Paper Strip That Could Have Turned Covid's CurveGuest Michael Mina · Host Lex FridmanHarvard immunologist Michael Mina tells Lex Fridman why twice-weekly antigen tests could have reversed the pandemic—and why regulation, not manufacturing, blocked them.
3:39:01ENMatthew Johnson on loosening the priors that run a human lifeGuest Matthew Johnson · Host Lex FridmanThe Johns Hopkins psychiatrist walks Lex Fridman through receptors, addiction, DMT entities, a 15-person smoking trial, and why psychedelics have taught us almost nothing about the hard problem of consciousness.
2:01:07ENMichael Littman isn’t waiting for a runaway god. He’s watching us.Guest Michael Littman · Host Lex FridmanThe Brown reinforcement-learning researcher tells Lex Fridman why accidental superintelligence feels like a 747 assembling itself — and why social media, rote language, and theory of mind worry him more.
2:59:53ENFor Every Triumph, Many Souls Must Be TrampledGuest John Clarke · Host Lex FridmanJohn Clarke, Lex Fridman's jiu-jitsu coach, on why most people who train are not martial artists, and what excellence actually costs.
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