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1:51:01ENJames Gosling Built Java to Make Pointer Bugs Impossible. Chrome Still Has Them.Guest James Gosling · Host Lex FridmanIn a 2020 conversation with Lex Fridman, Java’s designer traces a line from a neglected PDP-8 to Emacs, the JVM, and a thirty-year war on memory errors.
2:08:26ENSatisfying Lectures Don't Stick: Grant Sanderson on Feynman, Fear, and Hitting PublishGuest Grant Sanderson · Host Lex FridmanThe 3Blue1Brown creator talks with Lex Fridman about why the nicest explanations can fail, why he envies Bell Labs, and why the experts most qualified to teach are the ones least willing to post.
2:48:46ENLet Physics Walk: Russ Tedrake on Underactuated Robots, Contact, and Barefoot CommutesGuest Russ Tedrake · Host Lex FridmanMIT’s Russ Tedrake talks with Lex Fridman about gravity-powered walkers, a dead trout that swims upstream, why contact still breaks classical control, and what the DARPA Robotics Challenge taught him about testing.
1:43:10ENKen Thompson's Wife Left for Three Weeks. He Wrote Unix.Guest Brian Kernighan · Host Lex FridmanBrian Kernighan walks Lex Fridman through Bell Labs, C, AWK, AMPL, and a lifetime of tools that millions of people still run — including all of his mistakes.
1:49:51ENThe Idea Once Called a Devolution Now Powers Almost Every New ChipGuest David Patterson · Host Lex FridmanTuring Award winner David Patterson talks with Lex Fridman about RISC, RAID, Moore's Law, open hardware, and why chips without a software stack die.
4:08:58ENThe Man Who Named AGI Wants Superintelligence Raised on CompassionGuest Ben Goertzel · Host Lex FridmanLex Fridman talks with Ben Goertzel for four hours about OpenCog, Sophia, SingularityNET, and why a bigger neural net is not a mind.
51:14ENTrust, Then Verify: How Square Let 99 Percent of Merchants InGuest Jack Dorsey · Host Lex FridmanJack Dorsey tells Lex Fridman why Square is an access company, why the internet needs a native currency, and why self-awareness is being outsourced to algorithms.
2:09:02ENA Hundred-Nanometer Machine That Is Not Quite AliveGuest Dmitry Korkin · Host Lex FridmanDmitry Korkin walks through the structural genomics of SARS-CoV-2, from spike-ACE2 docking to drug-binding sites, vaccines, and cruise-ship simulations, recorded in the first spring of the pandemic.
17:19ENMoney Is a Game of Points: Vitalik Buterin on Coordination, Public Goods, and Quadratic FundingHost Lex FridmanVitalik Buterin explains money as a social point system, why value can survive without physical backing, and how quadratic funding tries to fix public-good underfunding.
1:35:04ENSatoshi Vanished. Vitalik Stayed Behind to Finish the Other Half.Guest Vitalik Buterin · Host Lex FridmanVitalik Buterin tells Lex Fridman what money actually is, what Satoshi invented, and why Ethereum is trying to become more than a points game.
1:13:51ENAnswering Questions Without Seeing the Data: Andrew Trask on the Privacy-Preserving AI StackHost Lex FridmanA tour of remote execution, differential privacy, secure multiparty computation, and the societal consequences of making private data usable.
49:53ENGilbert Strang still teaches with thick chalk and four subspacesGuest Gilbert Strang · Host Lex FridmanThe MIT linear-algebra legend talks with Lex Fridman about OpenCourseWare, singular values, neural nets as a million folds, and why calculus hogged the undergraduate timetable.
1:47:13ENWhen You Hit the Brakes, a Computer Is in the WayGuest Bjarne Stroustrup · Host Lex FridmanBjarne Stroustrup on why C++ still sits between the pedal and the pads, and why an abstraction that costs extra has no place in the language.
1:59:37ENLane Centering Is the Only Self-Driving Feature That Already HelpsGuest George Hotz · Host Lex Fridmancomma.ai founder George Hotz tells Lex Fridman why staying in the lane beats Level 5 promises, and why a robotaxi stack still has no network effect.
1:10:58ENThe Hadoop Lesson That Made Google Give TensorFlow AwayGuest Rajat Monga · Host Lex FridmanIn November 2015, Google put its core internal machine-learning system on GitHub. Rajat Monga explains why a company of that size would hand over the hard-to-copy part.
1:13:06ENThe Compiler That Got Apple, Google, and Intel to Share a CodebaseGuest Chris Lattner · Host Lex FridmanChris Lattner walks through LLVM, Clang, Swift, TPU numeric formats, and why compiler work is mostly software engineering.
1:20:09ENStack Overflow Was Never Designed for BeginnersGuest Jeff Atwood · Host Lex FridmanOn Stack Overflow’s tenth birthday, Jeff Atwood talks with Lex Fridman about puzzles, leadership, Discourse, and why a software team’s health is how fast it can change one word.
1:26:44ENHe raised Python like a child, then set it freeGuest Guido van Rossum · Host Lex FridmanIn a 2018 conversation with Lex Fridman, Guido van Rossum traces Python from electronics kits and Conway's Game of Life to the Thursday morning he resigned as benevolent dictator for life.
1:00:51ENInflict Pain, But Do It With a Smile: Julia Schottenstein on dbt's Rise and the Art of Getting AcquiredGuest Julia Schottenstein · Host Lenny RachitskyA former NEA investor turned dbt Cloud product leader explains why dbt won, how to approach M&A and pricing, and how venture habits make her a better PM.
1:05:22ENBuild First, Optimize Later: Harrison Chase on LangChain, Evals, and the State-Machine Future of AgentsHost Jacob EffronHarrison Chase explains how LangChain grew from an orchestration layer into LangSmith and LangGraph, why evaluation datasets force product clarity, and why reliable agents look more like state machines than autonomous loops.
56:20ENBiohub's Bet: Building Open AI World Models of Biology From Proteins Up to CellsHost Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.
1:11:06ENReplit's Amjad Masad on Building Your Own Model, Latency, and the Next Billion Software CreatorsHost Jacob EffronThe Replit founder explains why AI should be native to the product, why he trained a small in-house model, and why he thinks software engineering is about to split in two.
40:00ENThe Winds of Change: How Mistral Plans to Win the Open-Model EraHost Jacob EffronArthur Mensch explains Mistral's open-source strategy, enterprise distribution, model research, and views on AI regulation and sovereignty.
1:12:15ENThe Open-Model Vibe Check: China, Containment, and the Data MoatHost Jacob EffronJacob Effron and guests debate Chinese open-weight models, distillation, containment policy, the OpenAI–Hugging Face incident, and Cursor's data advantage.
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