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59:26ENAndy Ray on FPGAs, Hardware Design and HardcamlYaron Minsky, Andy Ray · Jane StreetJane Street’s hardware design lead explains why programmable circuits can improve performance and how software tooling makes them easier to build and test.
4:23:39ENThe Universe's Rule Might Fit on a PostcardGuest Stephen Wolfram · Host Lex FridmanStephen Wolfram tells Lex Fridman how a short computational rule on a hypergraph could generate space, time, relativity, and quantum mechanics.
2:10:53ENAll Your DNA Would Reach Jupiter a Hundred Times OverGuest Manolis Kellis · Host Lex FridmanManolis Kellis talks Lex Fridman through the epigenome, Neanderthals, Europa, midlife, and why "are you happy?" is the wrong question.
1:16:15ENAll-In E7: California, Gig Work and the SPAC BoomHost Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergFour investors debate California policy, police reform, markets and the 2020 election.
3:56:24ENThe Tic-Tac Knew We Were ThereGuest David Fravor · Host Lex FridmanNavy commander David Fravor tells Lex Fridman what four Super Hornet aircrew saw off the USS Nimitz in 2004, why he does not buy a secret human aircraft, and how an unexplained object never made anyone's to-do list.
3:01:07ENLoneliness Has No Clinic. Eugenia Kuyda Built an AI Friend AnywayGuest Eugenia Kuyda · Host Lex FridmanThe Replika co-founder talks with Lex Fridman about grief, conversation, and why memory—not a clever reply—is the real limit of AI companionship.
2:34:20ENIntelligence Is How Efficiently You Acquire Skills You Were Not Prepared ForGuest François Chollet · Host Lex FridmanFrançois Chollet tells Lex Fridman why skill is not intelligence, why GPT-3 is still pattern matching, and why a grid puzzle called ARC still separates children from machines.
1:41:24ENA child can lose half a brain. The rest will rewire around the jobGuest David Eagleman · Host Lex FridmanNeuroscientist David Eagleman tells Lex Fridman why the human brain is not hardware running software, but a livewired system that never stops physically reshaping itself.
2:08:26ENSatisfying Lectures Don't Stick: Grant Sanderson on Feynman, Fear, and Hitting PublishGuest Grant Sanderson · Host Lex FridmanThe 3Blue1Brown creator talks with Lex Fridman about why the nicest explanations can fail, why he envies Bell Labs, and why the experts most qualified to teach are the ones least willing to post.
2:56:24ENIt Is Knowing We Will Die That Makes Us HumanGuest Sheldon Solomon · Host Lex FridmanSheldon Solomon tells Lex Fridman how death anxiety, from an eight-year-old's stamp collection to 28-millisecond lab primes, quietly runs politics, religion, and everyday life.
1:41:35ENThe Smallest Lights: Sara Seager on Finding Life Beyond the SunGuest Sara Seager · Host Lex FridmanThe MIT planetary scientist talks with Lex Fridman about exoplanets, biosignature gases, a flower-shaped starshade, and the grief that sent her looking for another Earth.
2:10:06ENYou Might Have to Understand the World to Understand the Letter AGuest Dileep George · Host Lex FridmanDileep George on recursive cortical networks, why a five-year-old can read any new CAPTCHA, and what the Wright brothers actually learned from birds.
2:48:46ENLet Physics Walk: Russ Tedrake on Underactuated Robots, Contact, and Barefoot CommutesGuest Russ Tedrake · Host Lex FridmanMIT’s Russ Tedrake talks with Lex Fridman about gravity-powered walkers, a dead trout that swims upstream, why contact still breaks classical control, and what the DARPA Robotics Challenge taught him about testing.
2:29:24ENWe Are the Descendants of the First Digital ComputerGuest Manolis Kellis · Host Lex FridmanMIT computational biologist Manolis Kellis tells Lex Fridman why life is digital, why any two humans are 99.9 percent identical, and what evolutionary signatures reveal inside SARS-CoV-2.
1:34:10ENAll-In E6: Antitrust, Startup Acquisitions and Platform SpeechHost Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergA July 2020 debate on Big Tech hearings, marketplace power and the presidential election.
2:01:15ENNobody Died from the Fukushima ReactorsGuest Ian Hutchinson · Host Lex FridmanMIT plasma physicist Ian Hutchinson on fusion, a hundredfold carbon cut, scientism, and why faith is more than believing unproven claims.
2:07:32ENRichard Karp: Either All These Problems Are Easy, or None of Them AreGuest Richard Karp · Host Lex FridmanThe Turing Award winner walks Lex Fridman from a geometry proof that stopped him at 13 through NP-completeness, randomized algorithms, and why no program yet outthinks a six-month-old.
11:41ENFive Ways to Calculate the Wait for a Successful ShotSawyer · Jane StreetA 20% success rate leads to an expected wait of five attempts—but two consecutive successes take 30. Explore the reasoning through series, recursion and a long-run argument.
1:41:37ENThe Fallacy of the Successful First Step: Jitendra Malik on Why Seeing Still Isn't SolvedGuest Jitendra Malik · Host Lex FridmanBerkeley's Jitendra Malik tells Lex Fridman why computer vision keeps underestimating itself, why full self-driving still needs cognition, and why vision is the parent of language.
3:40ENBrian Kernighan on JavaScript and Software DependenciesGuest Brian Kernighan · Host Lex FridmanA 2020 conversation about language evolution and package complexity.
1:43:10ENKen Thompson's Wife Left for Three Weeks. He Wrote Unix.Guest Brian Kernighan · Host Lex FridmanBrian Kernighan walks Lex Fridman through Bell Labs, C, AWK, AMPL, and a lifetime of tools that millions of people still run — including all of his mistakes.
10:32ENReal Numbers: Expected Time Between Exams and a Half-Court Shot ChallengeSawyer · Jane StreetSawyer solves an exam-scheduling problem in several ways, then asks how many basketball attempts it takes to make one shot or two in a row.
1:37:31ENThe Robot That Brought the Beer Was Being TeleoperatedGuest Sergey Levine · Host Lex FridmanSergey Levine tells Lex Fridman why hardware is almost closed, why common sense has to be lived, and why offline reinforcement learning is the missing on-ramp from logs to robots that keep getting better.
6:04ENFinals Week and the Expected Number of Snowboards UsedSawyer · Jane StreetSawyer poses a new exam-scheduling puzzle and uses indicator variables in two ways to solve the previous snowboard problem.
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