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39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 15, 2026Podcast · 2 speakersThe Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of CybersecurityHost Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.
1:01:27ENNo Priors: AI, Machine Learning, Tech, & Startups· Jul 2, 2026Podcast · 2 speakersTwo Years and Four Months to a Live Reactor: Valar Atomics Wants Energy Ten Times CheaperHost Sarah Guo, Elad GilIsaiah Taylor walks Sarah Guo through Ward 250 in Utah and argues that nuclear is a hardware-iteration problem, not a paper-design one.
36:19ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 26, 2026Podcast · 2 speakersThe Benchmark Grid Is Broken: Why Test-Time Compute Has Outrun How We Score ModelsHost Sarah Guo, Elad GilOpenAI researcher Noam Brown argues that static leaderboards hide how long a model is allowed to think — and that safety evals, research taste, and the release cycle have not caught up.
41:09ENNo Priors: AI, Machine Learning, Tech, & Startups· May 28, 2026Podcast · 2 speakersAfter Agents Leak Tokens and Wipe Databases, Onyx Trains Small Models to Watch the Big OnesHost Sarah Guo, Elad GilTwo years ago enterprise security buyers told Maxim Bar Kogan he was too early. Now Fortune 10 companies are calling a sub-100-person Israeli startup because they cannot stop agent adoption — only reduce the chance the next action is illegitimate.
18:59ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 31, 2025Podcast · 2 speakers86 Out of 100: The Clips No Priors Could Not Leave on the Cutting-Room FloorHost Sarah Guo, Elad GilSarah Guo and Elad Gil stitch nine 2025 conversations into one short tour of legal AI, spatial intelligence, jobs, deterrence, and a doctor who made it home for dinner.
58:21ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 4, 2025Podcast · 2 speakersAttacks Take 23 Minutes. Response Still Takes Days.Host Sarah Guo, Elad GilPalo Alto Networks CEO Nikesh Arora on how AI is remaking search, enterprise software, and the timeline of a cyberattack.
41:25ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 12, 2025Podcast · 2 speakersBen Mann thinks superintelligence by 2028 is quite possibleHost Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.
30:46ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 24, 2025Podcast · 2 speakersDeep Research Turned Web Browsing into a Trainable ProblemHost Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.
36:24ENNo Priors: AI, Machine Learning, Tech, & Startups· Mar 5, 2025Podcast · 2 speakersThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesHost Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.
44:30ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 24, 2024Podcast · 2 speakers100,000 Rides a Week, Six Times Fewer Airbag Crashes: Waymo’s Co-CEO on Eighteen Years of Full AutonomyHost Sarah Guo, Elad GilDmitri Dolgov tells No Priors how a dozen Googlers, ten 100-mile routes, and a 2013 refusal to settle for driver assist became a rider-only service with an insurer-audited safety record.
37:47ENNo Priors: AI, Machine Learning, Tech, & Startups· Aug 30, 2024Podcast · 2 speakersWorking Backwards from AGI: Magic's Five-Million-Token BetHost Sarah Guo, Elad GilEric Steinberger wants a coding colleague you trust like a teammate — and a world that is still a good place thirty years after AGI.
31:24ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 25, 2024Podcast · 2 speakersSora's Leads: A Minute of HD Video Is Just the GPT-1 of Video ModelsHost Sarah Guo, Elad GilAditya Ramesh, Tim Brooks, and Bill Peebles tell No Priors why text-to-video sits on the path to AGI, why they started from scratch instead of extending an image generator, and why they still have no product date.
19:10ENNo Priors: AI, Machine Learning, Tech, & Startups· Jan 11, 2024Podcast · 2 speakersThe World's Only Capped-Profit CompanyHost Sarah Guo, Elad GilNo Priors looks back at 2023 through eight conversations on money, intelligence, jobs, and who should put the guardrails on a model.
32:57ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 9, 2023Podcast · 2 speakersA 7-billion-parameter model on a MacBook: Mistral's CEO reruns the cost of AIHost Sarah Guo, Elad GilArthur Mensch tells No Priors why Chinchilla made small models valuable, why open-sourcing Mistral 7B is not a bioweapon risk, and why guardrails belong on the application.
41:58ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 2, 2023Podcast · 2 speakersReliability is the bottleneck. Autonomy is what would make AI feel alive.Host Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.
32:34ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 23, 2023Podcast · 2 speakersTen Thousand Certified Engineers in a Year: Google Cloud's Order of Operations for Enterprise AIHost Sarah Guo, Elad GilKawal Gandhi, head of generative AI in Google Cloud's Office of the CTO, walks Sarah Guo and Elad Gil through dogfooding, the efficiency-productivity-creativity ladder, and why customer weights are the IP that cannot leak.
47:42ENNo Priors: AI, Machine Learning, Tech, & Startups· Aug 17, 2023Podcast · 2 speakersSal Khan Thinks Every Child Can Finally Have a TutorHost Sarah Guo, Elad GilThe Khan Academy founder tells Sarah Guo and Elad Gil how a family tutoring side project became an AI teaching assistant, and why he believes education is on the cusp of its biggest positive shift.
50:07ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 1, 2023Podcast · 2 speakersCheap Volume Beats Gold-Plated Jets: Anduril’s Brian Schimpf on AI and DefenseHost Sarah Guo, Elad GilThe Anduril CEO on Lattice, a school-bus-sized autonomous submarine, why Ukraine made fighter attrition unworkable, and how you actually sell a capability to the Pentagon.
42:18ENNo Priors: AI, Machine Learning, Tech, & Startups· May 18, 2023Podcast · 2 speakersTen Percent of Search Is Health — and the Doctor Is Googling TooHost Sarah Guo, Elad GilGoogle researcher Karan Singhal on Med-PaLM 2, the real bar for medical language models, and why medicine is a harder alignment lab than chatbots.
45:27ENNo Priors: AI, Machine Learning, Tech, & StartupsPodcast · 2 speakersThe Agent State: How AI Flattened the Adversary Pyramid and Why Defenders Need Their Own Frontier ModelsHost Sarah Guo, Elad GilCrowdStrike CEO George Kurtz explains how low-skill attackers now wield nation-state tradecraft through AI agents, and how CrowdStrike and Nvidia are training security-specific models to fight back.
26:01ENNo Priors: AI, Machine Learning, Tech, & StartupsPodcast · 2 speakersAfter the OpenAI Saga: Governance, Incentives, Diffusion Models and Why Your ASP Is My OpportunityHost Sarah Guo, Elad GilIn a host-only episode, Sarah Guo and Elad Gil unpack what OpenAI's leadership turmoil teaches about governance and incentives, then turn to AI video, small teams and the economics of AI investing.
33:31ENNo Priors: AI, Machine Learning, Tech, & StartupsPodcast · 2 speakersOpen Source Catches Up, Regulation Can Wait: Sarah Guo and Elad Gil Answer Listener QuestionsHost Sarah Guo, Elad GilTwo AI investors cover open-source models, autonomous agents, whether to regulate AI, where startups can win, and why healthcare innovation is so hard.
41:23ENNo Priors: AI, Machine Learning, Tech, & StartupsPodcast · 2 speakersThe Vulnerability Flood: Cloudflare's CTO on Security, Agent Traffic and an AI-First CompanyHost Sarah Guo, Elad GilCloudflare CTO Dane Knecht tells Sarah Guo how AI is accelerating vulnerability discovery, why agents need a new economic model for the web, and how Cloudflare is reorganizing around AI.