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31:22EN
No Priors: AI, Machine Learning, Tech, & Startups· Sep 18, 2025Podcast · 2 speakersDecagon Prices AI Support by the Conversation. The Market Is Wages.Host Sarah Guo, Elad GilJesse Zhang on six-figure contracts at zero ARR, 60–70% contact-center cuts, and a world where your agent calls the airline’s agent.
58:25ENNo Priors: AI, Machine Learning, Tech, & Startups· Sep 15, 2025Podcast · 2 speakersA construction permit that took four months now takes three minutesHost Sarah Guo, Elad GilJared Kushner talks with Sarah Guo and Elad Gil about Affinity Partners, the AI firm BrainCo, and how capital, energy, and Middle East diplomacy now run through AI.
44:44ENNo Priors: AI, Machine Learning, Tech, & Startups· Jul 10, 2025Podcast · 2 speakers$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsHost Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.
49:27ENNo Priors: AI, Machine Learning, Tech, & Startups· Jul 3, 2025Podcast · 2 speakersFrom 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt EngineeringHost Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.
45:21ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 17, 2025Podcast · 2 speakersApplied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and TanksHost Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.
25:13ENNo Priors: AI, Machine Learning, Tech, & Startups· May 29, 2025Podcast · 2 speakersThe AI Table Is Being Cleared: Two or Three Coding Winners, and Forty Years Without a Biotech GiantHost Sarah Guo, Elad GilSarah Guo and Elad Gil walk through which AI markets have already consolidated, why rival startups still refuse to merge, and the biotech science sitting unused.
31:34ENNo Priors: AI, Machine Learning, Tech, & Startups· May 15, 2025Podcast · 2 speakersOne Company Now Holds as Many Documents as the Entire Early WebHost Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.
40:54ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 17, 2025Podcast · 2 speakersDiscovery rates collapsed tenfold. KoBold still found a 5% copper depositHost Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.
40:33ENNo Priors: AI, Machine Learning, Tech, & Startups· Feb 27, 2025Podcast · 2 speakersModerna was only company 18. The real product is the company factoryHost Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.
38:14ENNo Priors: AI, Machine Learning, Tech, & Startups· Feb 20, 2025Podcast · 2 speakersKyle Vogt Pitched 120 Investors for Cruise. He Will Not Sell the Home-Robot CompanyHost Sarah Guo, Elad GilThe Twitch and Cruise co-founder tells Sarah Guo and Elad Gil why Tesla won on business model, why chores should be automated, and why a tiny AI-era team is enough.
49:36ENNo Priors: AI, Machine Learning, Tech, & Startups· Feb 14, 2025Podcast · 2 speakers86 Out of 100: Harvey's Playbook for Selling AI Into LawHost Sarah Guo, Elad GilWinston Weinberg on a Reddit blind test, expanding-and-collapsing product design, and why Harvey started with century-old firms instead of the mid-market.
23:37ENNo Priors: AI, Machine Learning, Tech, & Startups· Jan 9, 2025Podcast · 2 speakersA Hundred GPUs in Seconds: Why Modal Threw Out Docker and KubernetesHost Sarah Guo, Elad GilErik Bernhardsson tells Elad Gil that AI inference is too bursty for year-long GPU contracts, and that the cloud should feel as fast as a laptop.
31:18ENNo Priors: AI, Machine Learning, Tech, & Startups· Dec 19, 2024Podcast · 2 speakersElias Torres sold a billion-dollar company and called it a failure. Agency is the redo.Host Sarah Guo, Elad GilThe Drift founder wants $1 billion in revenue with 100 people, one email address, and software that works like a text to someone who actually shows up.
31:29ENNo Priors: AI, Machine Learning, Tech, & Startups· Sep 25, 2024Podcast · 2 speakersRippling skipped the chatbot and stamped employees after 90 days of workHost Sarah Guo, Elad GilCOO Matt MacInnis tells No Priors how Talent Signal reads source code, tickets, and customer conversations, then gives managers one calibrated label: high potential, typical, or pay attention.
48:20ENNo Priors: AI, Machine Learning, Tech, & Startups· Aug 15, 2024Podcast · 2 speakersNot Spending $100 Is a Hundred Times Better Than a Dollar BackHost Sarah Guo, Elad GilRamp co-founders Eric Glyman and Karim Atiyeh walk through self-driving money, Iron Man suits for sales, and why they never lead with the word AI.
41:25ENNo Priors: AI, Machine Learning, Tech, & Startups· Jul 25, 2024Podcast · 2 speakersEven If the Models Froze Today, We've Extracted One-Millionth of the ValueHost Sarah Guo, Elad GilAirtable CEO Howie Liu on why a 2012 vision deck still maps the company, why enterprise AI is stuck on imagination, and why codegen will not kill no-code before AGI.
29:12ENNo Priors: AI, Machine Learning, Tech, & Startups· Jul 18, 2024Podcast · 2 speakersGoldman says AI will touch 5% of tasks. Two investors take the report apartHost Sarah Guo, Elad GilSarah Guo and Elad Gil use a host-only No Priors episode to dismantle a June 2024 Goldman Sachs note, then map where they would buy, incubate, and hold.
39:59ENNo Priors: AI, Machine Learning, Tech, & Startups· May 23, 2024Podcast · 2 speakersFrom $6 million to $30 million ARR in three months: Garry Tan on YC’s AI boomHost Sarah Guo, Elad GilThe Y Combinator president tells Sarah Guo and Elad Gil why this batch looks like nothing he has seen in twenty years, and why a weak elephant is good news for startups.
38:01ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 4, 2024Podcast · 2 speakersHalf of GDP Is Labor. Figure Wants Humanoids to Do the Work.Host Sarah Guo, Elad GilBrett Adcock tells No Priors why a 21-month-old company raised $675 million to put general-purpose humanoid robots in factories first, then homes.
36:31ENNo Priors: AI, Machine Learning, Tech, & Startups· Mar 14, 2024Podcast · 2 speakersFigma's One-Way Door Swung Open — With a Billion-Dollar ConsolationHost Sarah Guo, Elad GilAfter regulators killed the Adobe deal, Dylan Field tells No Priors how Figma kept building, where AI belongs in design, and why the company was never meant to be only a design tool.
19:10ENNo Priors: AI, Machine Learning, Tech, & Startups· Jan 11, 2024Podcast · 2 speakersThe World's Only Capped-Profit CompanyHost Sarah Guo, Elad GilNo Priors looks back at 2023 through eight conversations on money, intelligence, jobs, and who should put the guardrails on a model.
36:22ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 26, 2023Podcast · 2 speakersOne Attacker and a For Loop: Why Email Is Still the Softest Target in an AI Arms RaceHost Sarah Guo, Elad GilMaterial Security co-founder Ryan Noon on how 2016 election hacks, Google and Microsoft's email duopoly, and large language models are rewriting both sides of cybersecurity.
43:07ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 12, 2023Podcast · 2 speakersThe VCs All Asked Who Else Had Done It. HubSpot’s Answer Was Intuit.Host Sarah Guo, Elad GilBrian Halligan walks through two decades of category creation, a CRM pivot nobody wanted, and why he thinks incumbents — not startups — win this AI round.
37:01ENNo Priors: AI, Machine Learning, Tech, & Startups· Sep 28, 2023Podcast · 2 speakersDNA Is Code, but You Compile It with a PipetteHost Sarah Guo, Elad GilGinkgo Bioworks CEO Jason Kelly tells No Priors why cells are worth the magic, why biology has no AWS, and why a pandemic should look like cybersecurity.Load moreShowing 24 of 65