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43:45ENEight Years of No Growth, Then OpenAI and NVIDIA Became His CustomersModeration: Sarah Guo, Elad GilWeights & Biases CEO Lukas Biewald tells No Priors how a labeling company with no chasm to cross funded the ML developer tools that trained most of the large language models.
46:57EN95% of Drug Programs Fail. Daphne Koller Is Betting Machine Learning on the First DecisionModeration: Sarah Guo, Elad GilA new medicine still takes more than a decade and well over a billion dollars — and Insitro's founder argues the expensive failures start with the wrong target, indication, or patient.
2:31:57ENJay McClelland on How Thought Emerges From Neural NetworksGast: Jay McClelland · Moderation: Lex FridmanThe Stanford cognitive scientist talks with Lex Fridman about connectionism, backpropagation, David Rumelhart, and why intuition discovers what logic later proves.
2:51:33ENThe Self Is a GPT Prompt: Wojciech Zaremba on Consciousness, Codex, and Fermi's SilenceGast: Wojciech Zaremba · Moderation: Lex FridmanOpenAI co-founder Wojciech Zaremba tells Lex Fridman he thinks we might be alone in the universe — and that GPT-3, Codex, and a one-handed robot already hint at how intelligence is built.
2:18:29ENYour Cortex Is 150,000 Brains Voting on a Coffee CupGast: Jeff Hawkins · Moderation: Lex FridmanJeff Hawkins tells Lex Fridman that intelligence is learning a model of the world, the neocortex is tens of thousands of independent maps that vote, and the fastest path to machine intelligence is reverse-engineering that sheet.
2:30:30ENThe Fallacy of the Successful First StepGast: Ishan Misra · Moderation: Lex FridmanBerkeley's Jitendra Malik explains why computer vision still looks easy, why fully autonomous driving is not near, and what children know that today's networks do not.
1:56:17ENIf You Reran Earth a Million Times, Would Anything Like Us Appear?Gast: Risto Miikkulainen · Moderation: Lex FridmanRisto Miikkulainen on neuroevolution, hyena raids, basil that never sleeps, and why variation-plus-selection still finds solutions backpropagation cannot see.
1:49:56ENA 21-Year-Old at a Party Called GameStop. He Was Right.Gast: Richard Craib · Moderation: Lex FridmanNumerai founder Richard Craib talks with Lex Fridman about WallStreetBets, crowdsourced machine learning, and why finance is a machine for pulling the future into the present.
2:01:07ENMichael Littman isn’t waiting for a runaway god. He’s watching us.Gast: Michael Littman · Moderation: Lex FridmanThe Brown reinforcement-learning researcher tells Lex Fridman why accidental superintelligence feels like a 747 assembling itself — and why social media, rote language, and theory of mind worry him more.
2:28:11ENPeople Are Easy to Predict — and They Hate Being Told SoGast: Charles Isbell · Moderation: Lex FridmanGeorgia Tech dean Charles Isbell talks with Lex Fridman about interactive AI, computing as a mindset, and race in America.
2:34:20ENIntelligence Is How Efficiently You Acquire Skills You Were Not Prepared ForGast: François Chollet · Moderation: Lex FridmanFrançois Chollet tells Lex Fridman why skill is not intelligence, why GPT-3 is still pattern matching, and why a grid puzzle called ARC still separates children from machines.
1:37:31ENThe Robot That Brought the Beer Was Being TeleoperatedGast: Sergey Levine · Moderation: Lex FridmanSergey Levine tells Lex Fridman why hardware is almost closed, why common sense has to be lived, and why offline reinforcement learning is the missing on-ramp from logs to robots that keep getting better.
2:00:32ENSlow Synapses Grow Fast Learners — Warmth Is the Harder ProblemGast: Matt Botvinick · Moderation: Lex FridmanDeepMind neuroscience director Matt Botvinick tells Lex Fridman how prefrontal cortex, meta-reinforcement learning, and dopamine research meet the human question of what a better life with AI would actually look like.
1:37:28ENWe Are Still Massively Underestimating Deep LearningGast: Ilya Sutskever · Moderation: Lex FridmanIlya Sutskever tells Lex Fridman why 2012 was about conviction, why bigger models can get worse before they get better, and what he would do with an AGI.
1:12:03ENMice Don't Get Alzheimer's: Daphne Koller on Disease in a DishGast: Daphne Koller · Moderation: Lex FridmanThe Coursera co-founder and insitro CEO on why most diseases are not one disease, how to turn cells into data, and why overconfident neural nets can kill.
1:12:48ENJohn Hopfield's Physics of Mind: Glitches Become FeaturesGast: John Hopfield · Moderation: Lex FridmanThe Princeton physicist walks Lex Fridman from a wobbly London bridge to Hopfield networks, consciousness-as-story, and why his famous model still does not explain learning.
1:45:49ENPrediction is not a decision: Michael I. Jordan on markets and the unfinished AI revolutionGast: Michael I. Jordan · Moderation: Lex FridmanThe Berkeley statistician tells Lex Fridman that today's systems are a proto-engineering field, and that the hard work is connecting producers and consumers — not imitating minds.
1:44:55ENIf You Need 60,000 Digits, You Have Not Found IntelligenceGast: Vladimir Vapnik · Moderation: Lex FridmanVladimir Vapnik tells Lex Fridman that intelligence is the art of shrinking a sea of functions with a few good predicates — and that MNIST, solved with sixty examples per class, is the test.
1:18:41ENThe SS Soldier Who Hugged a Jewish Boy, and the Systems That Still Fool UsGast: Daniel Kahneman · Moderation: Lex FridmanDaniel Kahneman on System 1, deep learning that does not know what it is saying, and why a machine that must call a human is almost as hard as a machine that never needs one.
1:23:01ENYou Cannot Ask a Question You Have No Words ForGast: Judea Pearl · Moderation: Lex FridmanA teenager spent three days in bed with a fever after learning that geometry could be done in algebra — then spent a career giving cause and effect a mathematics.
35:46ENYou never hear structure: Noam Chomsky on language, cognition, and deep learningGast: Noam Chomsky · Moderation: Lex FridmanLex Fridman asks the linguist whether we could talk to aliens, how far language goes in the brain, and whether neural networks tell us anything about the mind.
49:53ENGilbert Strang still teaches with thick chalk and four subspacesGast: Gilbert Strang · Moderation: Lex FridmanThe MIT linear-algebra legend talks with Lex Fridman about OpenCourseWare, singular values, neural nets as a million folds, and why calculus hogged the undergraduate timetable.
1:48:55ENThree Fairness Rules That Cannot All Be TrueGast: Michael Kearns · Moderation: Lex FridmanMichael Kearns tells Lex Fridman why algorithmic fairness is messier than privacy, and why a Pareto curve belongs in front of the people who actually have to choose.
1:03:13ENYou Can't Have Both Kinds of Fairness, Says Peter NorvigGast: Peter Norvig · Moderation: Lex FridmanThe co-author of Artificial Intelligence: A Modern Approach walks Lex Fridman through recidivism scores, utility functions, Lisp, MOOCs, and why human-level intelligence should not be the goal.
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