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2:28:14EN
Lex Fridman· 23. Juli 2025Podcast · 2 StimmenNature Has Structure: Demis Hassabis on Learnable Reality and AGIGast: Demis Hassabis · Moderation: Lex FridmanThe Google DeepMind CEO argues that evolution-shaped systems can be modeled by classical learning, and that interactive world models sit on the path to AGI.
3:14:34ENLex Fridman· 14. Juni 2025Podcast · 2 StimmenIf ten things make a problem hard, Terence Tao turns nine of them offGast: Terence Tao · Moderation: Lex FridmanThe Fields Medalist walks Lex Fridman from the Kakeya needle and Navier-Stokes through Lean, Perelman, and why today's AI still cannot smell a dead-end proof.
3:19:21ENLex Fridman· 9. Dez. 2023Podcast · 2 StimmenComplexity without copies is just randomness: Lee Cronin on assembly theoryGast: Lee Cronin · Moderation: Lex FridmanThe Glasgow chemist walks Lex Fridman through his controversial Nature paper, a proposed life meter for other worlds, and the claim that the universe is too big to contain its own future.
2:18:25ENLex Fridman· 1. Sept. 2023Podcast · 2 StimmenGrow Everything: Neri Oxman on Giving Nature a VoteGast: Neri Oxman · Moderation: Lex FridmanThe designer-scientist who left MIT to build OXMAN talks silkworm pavilions, bees in space, and why the end of human agency might be the start of nature's.
2:07:04ENLex Fridman· 28. Mai 2023Podcast · 2 StimmenThe Ribosome Already Solved Digital ManufacturingGast: Neil Gershenfeld · Moderation: Lex FridmanNeil Gershenfeld tells Lex Fridman why Turing separated the head from the tape, how fab labs are the personal-computer moment for making things, and what it would take to grow a civilization from about twenty parts.
2:06:25ENLex Fridman· 19. Dez. 2022Podcast · 2 StimmenNathalie Cabrol Wants the Nature of Life, Not Just a Signal from MarsGast: Nathalie Cabrol · Moderation: Lex FridmanThe SETI Institute astrobiologist tells Lex Fridman why crater lakes, panspermia, and a Mandelbrot view of language all point to the same question: what life actually is.
3:43:01ENLex Fridman· 7. Sept. 2022Podcast · 2 StimmenPut Hydrogen and CO2 in a Tube. Thermodynamics Wants Cells. Nothing Happens.Gast: Nick Lane · Moderation: Lex FridmanBiochemist Nick Lane talks Lex Fridman through hydrothermal vents, mitochondria, sex, consciousness, and why bacteria should be common while civilizations are not.
2:13:16ENLex Fridman· 23. Juli 2022Podcast · 2 StimmenEvery Atom in Your Body Was Forged in a Dead StarGast: Martin Rees · Moderation: Lex FridmanMartin Rees talks Lex Fridman through dark matter, alien life, one-way Mars trips, and why this century is the first in which one species holds the planet.
2:10:39ENLex Fridman· 1. Juli 2022Podcast · 2 StimmenDemis Hassabis: Solve Intelligence, Then Solve Everything ElseGast: Demis Hassabis · Moderation: Lex FridmanThe DeepMind CEO tells Lex Fridman why the Turing Test is the wrong exam, how AlphaFold rewrote biology, and why the quiet radio sky suggests we are probably alone.
2:55:05ENLex Fridman· 8. Mai 2022Podcast · 2 StimmenExtinction awareness is the human trait Mason wants to carry to the starsGast: Chris Mason · Moderation: Lex FridmanCornell geneticist Chris Mason on why seeing our own end creates a duty to engineer life for other worlds — and what a 500-year plan would actually require.
3:05:24ENLex Fridman· 22. Sept. 2021Podcast · 2 StimmenTravis Oliphant wrote NumPy in an empty semester — and still wants open source to payGast: Travis Oliphant · Moderation: Lex FridmanThe creator of NumPy, SciPy, and Anaconda tells Lex Fridman how array thinking, a priced book, and the packaging wars shaped scientific Python.
3:02:43ENLex Fridman· 18. Jan. 2021Podcast · 2 StimmenHumanity Cannot Survive on the Right Person Showing Up at the Right TimeGast: Max Tegmark · Moderation: Lex FridmanMIT physicist Max Tegmark tells Lex Fridman why AI should be as well understood as rockets, why 2020 was a warning on weapons and news, and why luck is a terrible long-term plan.
2:17:42ENLex Fridman· 11. Jan. 2021Podcast · 2 StimmenThe building block of life is a bead on a string, not the whole proteinGast: Dmitry Korkin · Moderation: Lex FridmanDmitry Korkin tells Lex Fridman why protein domains, a triangular spike, and a conservative viral shell matter more than the AlphaFold headline, and why a Nobel laureate once answered a midnight forum post.
2:39:45ENLex Fridman· 25. Okt. 2020Podcast · 2 StimmenThe obesity gene was never the obesity geneGast: Manolis Kellis · Moderation: Lex FridmanManolis Kellis tells Lex Fridman how one nucleotide a million bases from FTO rewrote obesity biology, and why human genetics is now driving the study of disease.
2:29:24ENLex Fridman· 31. Juli 2020Podcast · 2 StimmenWe Are the Descendants of the First Digital ComputerGast: Manolis Kellis · Moderation: Lex FridmanMIT computational biologist Manolis Kellis tells Lex Fridman why life is digital, why any two humans are 99.9 percent identical, and what evolutionary signatures reveal inside SARS-CoV-2.
1:02:14ENLex Fridman· 30. Juni 2020Podcast · 2 StimmenThe 28-year wait: Robert Langer on rejection, polymers, and a thousand studentsGast: Robert Langer · Moderation: Lex FridmanThe MIT bioengineer talks with Lex Fridman about drug delivery, tissue engineering, patents, and the long path from a Folkman hypothesis to Avastin.
1:12:03ENLex Fridman· 5. Mai 2020Podcast · 2 StimmenMice Don't Get Alzheimer's: Daphne Koller on Disease in a DishGast: Daphne Koller · Moderation: Lex FridmanThe Coursera co-founder and insitro CEO on why most diseases are not one disease, how to turn cells into data, and why overconfident neural nets can kill.
2:09:02ENLex Fridman· 22. Apr. 2020Podcast · 2 StimmenA Hundred-Nanometer Machine That Is Not Quite AliveGast: Dmitry Korkin · Moderation: Lex FridmanDmitry Korkin walks through the structural genomics of SARS-CoV-2, from spike-ACE2 docking to drug-binding sites, vaccines, and cruise-ship simulations, recorded in the first spring of the pandemic.
39:33ENLex Fridman· 22. Nov. 2019Podcast · 2 StimmenMars is not Plan B: Dava Newman on spacesuits, autonomy, and Spaceship EarthGast: Dava Newman · Moderation: Lex FridmanThe MIT Apollo professor and former NASA deputy administrator on Magellan’s crew, mechanical counterpressure, and why the next decade belongs to Earth.
1:17:29ENLex Fridman· 23. Sept. 2019Podcast · 2 StimmenThe Algorithm Is Already Better. The Clinic Still Uses 1967.Gast: Regina Barzilay · Moderation: Lex FridmanMIT's Regina Barzilay on why deep learning already beats the breast-cancer 'density' score — and why data, liability, and incentives still will not move.
57:42ENLex Fridman· 12. Aug. 2019Podcast · 2 StimmenA Brain Organoid Is Not a BrainGast: Paola Arlotta · Moderation: Lex FridmanHarvard developmental biologist Paola Arlotta on how the cerebral cortex is built, why timing and mechanical force are part of the code, and why a dish of stem cells is only a window onto that process.
16:41ENLex FridmanPodcastAlphaFold 2 and the Protein-Folding Breakthrough: Why Lex Fridman Calls It a Landmark for AI and BiologyModeration: Lex FridmanA quick explainer on DeepMind's CASP14 result, how protein folding works, how AlphaFold 1 and 2 likely differ, and what the advance could unlock.