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57:47ENPeter Thiel on AI Acceleration, Global Power, and the Values of Its BuildersGast: Peter Thiel · Moderation: Walter IsaacsonWalter Isaacson challenges Peter Thiel on AI risk, concentrated power, and the moral responsibilities of visionary founders. Thiel argues that stopping progress carries dangers of its own.
45:08ENSam Altman on AI Discovery, Consciousness, Compute and a Human-Centered FutureMatthew Berman, Sam Altman · Forward FutureIn a conversation with Matthew Berman, Altman discusses scientific progress, personal assistants, recursive self-improvement and the importance of human agency.
37:14ENElon Musk on AI Control, Robot Abundance, and His Regrets About DOGEGast: Elon Musk · Moderation: Walter IsaacsonWalter Isaacson asks Elon Musk how humanity can remain safe and find purpose as AI grows more capable, and challenges him on politics, empathy, and the future he is building.
31:59ENClaude Opus 5.5: Benchmarks, Cost and Anthropic’s Approach to PacingMatthew Berman, Thariq · Forward FutureMatthew Berman reviews the release and speaks with Anthropic’s Thariq about daily workflows, evaluation and agent harnesses.
0:33ENAnthropic's IPO and AI Safety: A Question of ConsistencyMatthew Berman, Christian Catalini · Forward FutureIn a short interview excerpt, Matthew Berman and economist Christian Catalini question how a planned public offering relates to warnings about advanced AI risk.
44:28ENTibo on Coding Agents, Faster AI and OpenAI’s Product DirectionMatthew Berman, Thibault Sottiaux · Forward FutureOpenAI’s Tibo discusses agent interfaces, usage resets, model efficiency and the trade-offs behind faster inference.
32:22ENDemis Hassabis on AGI, Scientific Discovery and the Challenges AheadGast: Demis Hassabis · Moderation: Harry StebbingsThe Google DeepMind CEO discusses compute, continual learning, safety standards and his hopes for AI in science, medicine and energy.
1:14:39ENNick Frosst on Cohere’s Enterprise AI Strategy and the Limits of HypeGast: Nick Frosst · Moderation: Harry StebbingsThe Cohere co-founder discusses data, benchmarks, workplace automation and why he challenges popular claims about AGI.
1:16:25ENMartin Casado on AI Models, Open Technology and Venture CompetitionGast: Martin Casado · Moderation: Harry StebbingsThe Andreessen Horowitz partner discusses coding tools, open-model policy, labor disruption and how his firm evaluates investments.
1:03:46ENZico Kolter on AI Safety, Scaling and the Limits of Open ModelsGast: Zico Kolter · Moderation: Harry StebbingsThe Carnegie Mellon researcher and OpenAI board member explains why prompt injection worries him, how he thinks about open weights, and why AI progress remains uncertain.
50:20ENArvind Narayanan on AI Scaling, Real-World Risks and the Limits of Model BenchmarksGast: Arvind Narayanan · Moderation: Harry StebbingsThe Princeton professor challenges simple claims about scaling, AGI timelines and AI adoption while discussing deepfakes, healthcare, education and security.
8:37:34ENThe first Neuralink patient beat a world record with most of his electrodes goneGast: Elon Musk · Moderation: Lex FridmanLex Fridman talks with Elon Musk, the Neuralink team, and Noland Arbaugh about a wireless brain implant, the software that rescued it, and why bandwidth is Musk’s bet on living with AI.
59:24ENIf You Only Trust What You Can See, You Miss Most of the UniverseGast: Lisa Randall · Moderation: Lex FridmanHarvard physicist Lisa Randall talks with Lex Fridman about dark matter, dinosaur extinctions, the LHC, and why a theory is only as good as the measurement that can kill it.
4:27:46ENHalf a Million Girls in Wells, and We Still Change the ChannelGast: Sam Harris · Moderation: Lex FridmanSam Harris tells Lex Fridman why emotional contagion is a bad moral compass, why Trump broke norms more than laws, and why Twitter, COVID, and AGI all look like failures of seriousness.
3:35:40ENLiv Boeree on Moloch, Useful Fictions, and Why Luck Keeps Poker AliveGast: Liv Boeree · Moderation: Lex FridmanThe poker champion and science educator talks with Lex Fridman about game theory, attention, simulation, aliens, and the existential races that look like games nobody can quit.
1:09:14ENSuffering Is a State You'd Rather Not Be In — Peter Singer on Animals, Robots, and UsGast: Peter Singer · Moderation: Lex FridmanOn Lex Fridman's podcast, the Princeton bioethicist defines suffering, extends it from factory farms to possible machine minds, and still puts extreme poverty first.
2:12:36ENAttacks Climb the Stack Until They Land on PeopleGast: Dawn Song · Moderation: Lex FridmanDawn Song tells Lex Fridman why the next security crisis is human, how a sticker can rewrite a stop sign, and why data still has no property right.
1:39:57ENPeople Say They Want Perfect Robots. They Trust the Ones That Push BackGast: Ayanna Howard · Moderation: Lex FridmanAyanna Howard on human-robot interaction, the ethics of safety-critical code, and why a little imperfection is what actually earns trust.
1:48:55ENThree Fairness Rules That Cannot All Be TrueGast: Michael Kearns · Moderation: Lex FridmanMichael Kearns tells Lex Fridman why algorithmic fairness is messier than privacy, and why a Pareto curve belongs in front of the people who actually have to choose.
1:08:37ENA Bar in Montreal, Then a Night of Code: Ian Goodfellow on Why GANs WorkGast: Ian Goodfellow · Moderation: Lex FridmanLex Fridman talks with Ian Goodfellow about the 2014 invention of generative adversarial networks, adversarial examples as a security problem, and what still has to be built before machines can hold a fact the way a person does.
1:21:56ENWe Keep Waiting for AGI. Eric Weinstein Says Artificial Life Is Already HereGast: Eric Weinstein · Moderation: Lex FridmanOn the Lex Fridman Podcast, the mathematician and Thiel Capital managing director argues that selection without intelligence can already parasitize us, and that our bigger failure is wisdom that never caught up with the toys.
1:06:17ENLibratus Beat the World's Best Poker Players Without a Neural NetworkGast: Tuomas Sandholm · Moderation: Lex FridmanTuomas Sandholm tells Lex Fridman how game theory, abstraction, and search — not deep learning — took heads-up no-limit Texas Hold'em, and why the harder work is deploying that toolkit outside the casino.







