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38:14ENDiffusion Will Win Inference: Stefano Ermon Bets Parallel Tokens Beat Custom SiliconModeration: Sarah Guo, Elad GilThe Stanford diffusion pioneer tells No Priors why a 50-person lab is training language models that generate many tokens at once — and why that maps to GPUs the way transformers once mapped to training.
3:36:13ENNVIDIA’s Ming-Yu Liu on Cosmos, Physical AI, and Creating New MarketsGast: Ming-Yu Liu · Moderation: 张小珺NVIDIA research VP Ming-Yu Liu explains how a decade of generative-model research led to Cosmos 3, a world foundation model for Physical AI. He also shares what he learned from Jensen Huang about long-term bets, teamwork, and building markets instead of fighting over existing ones.
2:59:03ENYou Kaichao on How vLLM Grew from Open-Source Project to AI Infrastructure CompanyGast: You Kaichao · Moderation: 张小珺Inferact co-founder You Kaichao traces vLLM’s path from Berkeley research to a company, then explains why model, inference, hardware and agent design increasingly have to move together.
3:46:12ENKay Ke on Physical Intelligence, Robot Learning, and the Future of RoboticsGast: Kay Ke · Moderation: 张小珺Physical Intelligence researcher Kay Ke traces the field's research lineages and explains Pi's progression from π₀ to π*₀.₆. She also reflects on education, fiction, ambition, and what it means to build robots that work beyond a demo.
36:19ENThe Benchmark Grid Is Broken: Why Test-Time Compute Has Outrun How We Score ModelsModeration: Sarah Guo, Elad GilOpenAI researcher Noam Brown argues that static leaderboards hide how long a model is allowed to think — and that safety evals, research taste, and the release cycle have not caught up.
32:22ENDemis Hassabis on AGI, Scientific Discovery and the Challenges AheadGast: Demis Hassabis · Moderation: Harry StebbingsThe Google DeepMind CEO discusses compute, continual learning, safety standards and his hopes for AI in science, medicine and energy.
13:30ENHow AlphaGeometry Combines Logical Proof with Creative ConstructionAleph0Aleph0 explains how a symbolic geometry solver gets surprisingly far without AI, and how a language model supplies the auxiliary constructions that take it to Olympiad level.
42:09ENAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Moderation: Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.
3:14:34ENIf ten things make a problem hard, Terence Tao turns nine of them offGast: Terence Tao · Moderation: Lex FridmanThe Fields Medalist walks Lex Fridman from the Kakeya needle and Navier-Stokes through Lean, Perelman, and why today's AI still cannot smell a dead-end proof.
38:10ENo3 should wait exactly as long as the answer takesModeration: Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.
45:31ENJerry Chow on Quantum Computing, Encryption, AI and Error CorrectionMatthew Berman, Jerry Chow · Forward FutureIBM’s quantum systems director explains qubits, cryogenic hardware, software and the work needed to make quantum computers useful.
34:09ENFive Independent Teams Found the Same 10-to-1 Mix That Beats TransformersModeration: Sarah Guo, Elad GilThe authors of S4 and Mamba argue that mostly state-space layers plus a dash of attention is the architecture that actually works—and they are shipping it first as real-time speech.
26:00ENWhy a Zapier founder thinks AGI research has been stalled for four yearsModeration: Sarah Guo, Elad GilMike Knoop and François Chollet put more than a million dollars on beating ARC-AGI, the eval they say actually measures general intelligence.
2:15:39ENRoman Yampolskiy Puts Superintelligent Ruin at 99.99 PercentGast: Roman Yampolskiy · Moderation: Lex FridmanThe AI safety researcher tells Lex Fridman that controlling AGI is as impossible as a perpetual motion machine, and that tests, open source, and regulation cannot close the gap.
2:50:44ENThe Pirahã Have No Word for OneGast: Edward Gibson · Moderation: Lex FridmanMIT psycholinguist Ted Gibson tells Lex Fridman why related words sit together, why language is not thought, and why large language models ace form while missing meaning.
2:47:17ENIf You Want Human-Level AI, Abandon Generative ModelsGast: Yann Lecun · Moderation: Lex FridmanYann LeCun tells Lex Fridman why autoregressive LLMs cannot plan, remember, or understand the physical world — and why open source is the only democratic answer.
41:58ENReliability is the bottleneck. Autonomy is what would make AI feel alive.Moderation: Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.
39:50ENWhy AI Video Is Still a Four-Second CorgiModeration: Sarah Guo, Elad GilMeta research director Devi Parikh explains why text-to-video has stalled on short animated images, and what it will take to get past that plateau.
3:11:35ENSearch was always a hack: Marc Andreessen on AI, truth, and the next internetGast: Marc Andreessen · Moderation: Lex FridmanLex Fridman sits down with the Mosaic co-creator and Andreessen Horowitz founder to ask whether Google Search, the browser, and open-source AI survive the decade.
2:07:04ENThe Ribosome Already Solved Digital ManufacturingGast: Neil Gershenfeld · Moderation: Lex FridmanNeil Gershenfeld tells Lex Fridman why Turing separated the head from the tape, how fab labs are the personal-computer moment for making things, and what it would take to grow a civilization from about twenty parts.
4:14:33ENThe Next Token Is Not a Proof: Stephen Wolfram on ChatGPT and Computational TruthGast: Stephen Wolfram · Moderation: Lex FridmanIn his fourth conversation with Lex Fridman, Stephen Wolfram contrasts large language models with Wolfram|Alpha, then follows computational irreducibility from ChatGPT through observers, thermodynamics, and the three great theories of twentieth-century physics.
37:18ENUse Retrieval for a Wi-Fi Password. Use Experts for a Company's Private Language.Moderation: Sarah Guo, Elad GilGoogle Brain's Kelvin Guu on REALM, FLAN, model surgery, and why personalizing large models is still an unsolved interface problem.
2:27:58ENIt took Atlas fourteen years to walk the way Playter wantedGast: Robert Playter · Moderation: Lex FridmanBoston Dynamics CEO Robert Playter traces thirty years from a MIT basement pogo stick to Atlas, Spot, and Stretch — and why the company still designs machines that are allowed to fall.
2:30:28ENAI Only Has a Neocortex: Manolis Kellis on Evolutionary Baggage and Superintelligent PartnersGast: Manolis Kellis · Moderation: Lex FridmanOn his fifth Lex Fridman podcast, the MIT computational biologist argues that layered evolutionary history is what makes humans irreplaceable — and that alignment with AI has to run both ways.
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