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56:20ENBiohub's Bet: Building Open AI World Models of Biology From Proteins Up to CellsModeration: Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.
1:03:59ENBuilding a World Model of Life: Biohub's Alex Rives on Why Better Measurement Must Come Before Virtual CellsModeration: Nathan LabenzBiohub's head of science explains why today's virtual cell models fall short, how a $1.8 billion data push aims to fix it, and what a five-year information-level model of the cell could unlock.
1:03:24ENWhy Sora Bet on People, Not Just PixelsModeration: Jacob EffronThe Sora team explains how a video model became a social creation network, what cameos revealed about human creativity, and why the next frontier is world simulation.
17:40ENFrom AlphaGo Zero to MuZero: How Self-Play Strips Knowledge Out of AIModeration: Lex FridmanDeepMind's David Silver explains why removing human knowledge made AlphaZero stronger and more general, and how MuZero extended the idea to worlds with unknown rules.
1:13:40ENThe Long Tail, the World Model, and the 1995 Problem: Inside Waymo's Scaling Phase and Robotics' Missing MomentModeration: Jacob EffronVincent, a distinguished engineer at Waymo, explains how foundation models became teachers for self-driving, why the long tail and causality are the real frontier, and where robotics still lacks its generalist proof point.
1:19:34ENFei-Fei Li on ImageNet, World Models and Why Everyone Has a Role in AIModeration: Lenny RachitskyThe scientist often called the godmother of AI traces how big data sparked deep learning, explains why spatial intelligence is the next frontier, and shows what World Labs' first product, Marble, can do.
43:44ENRoblox's 20-Year Bet: Building the Holodeck with Native AI ModelsModeration: Sarah Guo, Elad GilRoblox CEO Dave Baszucki explains how 13 billion monthly hours of 3D interaction data could power smarter NPCs, virtual doppelgängers and a cloud-native future for games.
45:12ENInside a Robot Data Factory: How Mecka Sensorizes Humans to Train RobotsMecka AI founder Josh Gao explains how a company collects, quality-checks and licenses egocentric human data, and why robotics will arrive as a steady unlock of tasks rather than a single breakthrough.








