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1:23:46ENSurviving the Next Crisis: Waze Co-Founder Uri Levine on Cash Shocks, Lost Product-Market Fit and Never Giving UpGast: Uri Levine · Moderation: Lenny RachitskyUri Levine explains how founders should diagnose a startup crisis, act within days, keep their teams on board and decide whether to pivot or shut down.
1:03:59ENBuilding a World Model of Life: Biohub's Alex Rives on Why Better Measurement Must Come Before Virtual CellsModeration: Nathan LabenzBiohub's head of science explains why today's virtual cell models fall short, how a $1.8 billion data push aims to fix it, and what a five-year information-level model of the cell could unlock.
23:37ENPave Your Own Path: Lex Fridman on Impostor Syndrome, Envy and GratitudeModeration: Lex FridmanIn an Ask Me Anything episode, Lex Fridman answers listeners' questions about self-doubt by arguing against comparison, for finding your own passion, and for pairing self-criticism with gratitude.
18:45ENWhy Sean Carroll Thinks Many-Worlds Is the Cleanest Version of Quantum MechanicsGast: Sean Carroll · Moderation: Lex FridmanThe Caltech physicist explains how Everett's idea works, answers the energy-conservation objection, and compares it with its rivals.
1:13:13ENOKRs Are a Vitamin, Not a Medicine: Christina Wodtke on Making Goals Actually WorkGast: Christina Wodtke · Moderation: Lenny RachitskyThe Stanford lecturer and author of Radical Focus explains what OKRs are really for, why they fail, and how to run a healthy weekly cadence.
1:53:14ENWorth Thousands, Priced at $20: Zvi Mowshowitz on OpenAI's Flurry, Gemini Bets, Deepfakes and a Compute CapModeration: Nathan LabenzZvi Mowshowitz and Nathan Labenz survey OpenAI's launch spree, AI pricing and bundling, data pollution, deepfakes, the reversal curse, calls to cap training compute, and Amazon's Anthropic deal.
1:17:35ENStick With It: Chris Hutchins on Big Product Bets and Building a Top Business PodcastGast: Chris Hutchins · Moderation: Lenny RachitskyThe former Wealthfront product lead behind All the Hacks explains how to run bold bets inside a company and how to launch, grow and sustain a podcast.
1:21:38ENSearch Isn't Dying, It's Expanding: Robby Stein on Google's AI Mode and Building Products RelentlesslyGast: Robby Stein · Moderation: Lenny RachitskyGoogle Search's VP of Product explains how AI Overviews, Lens and AI Mode fit together, and the product principles he carried from Instagram Stories to Google.
1:03:24ENWhy Sora Bet on People, Not Just PixelsModeration: Jacob EffronThe Sora team explains how a video model became a social creation network, what cameos revealed about human creativity, and why the next frontier is world simulation.
1:30:36ENDon't Make Me Think: Stewart Butterfield on Utility Curves, Taste and the Case Against Removing FrictionGast: Stewart Butterfield · Moderation: Lenny RachitskyThe Flickr and Slack co-founder explains how he judged features, why comprehension matters more than click counts, and how large organizations drift into busywork.
1:52:49ENInside Anthropic's Growth Team: Big Bets, Automated Experiments and Firefighting SuccessModeration: Lenny RachitskyAmol Avasare, Anthropic's Head of Growth, explains how a roughly 40-person team handles hypergrowth, automates experimentation with Claude, and rethinks the PM and engineer ratio.
1:07:08ENIf the Model Is the Product, the Eval Is the PRD: Inside Mercor's RiseGast: Brendan Foody · Moderation: Lenny RachitskyMercor CEO Brendan Foody explains why AI labs will pay almost anything for expert-written evals, how his company grew from $1 million to a $400 million run rate in 16 months, and what that means for jobs and founders.
1:33:55ENGetting Startup Press Without a Rolodex: A Practical PR PlaybookGast: Emilie Gerber · Moderation: Lenny RachitskyPR agency founder Emilie Gerber walks through which outlets to target, how to write a three-sentence pitch, and how to judge whether press is worth the effort.
51:30ENLess Email, Better Thinking: Grammarly’s CEO on AI That Augments CommunicationModeration: Jacob EffronGrammarly CEO Rahul explains how the company is moving from grammar checks to end-to-end communication assistance—and why evals, user data, and measurable outcomes matter.
29:54ENSeven Levels of a Pandemic: Pain, Challenge and Hope From Biology to PhilosophyModeration: Lex FridmanLex Fridman maps the coronavirus onto seven levels of attack on society and proposes a response and a reason for hope at each one.
10:17ENWhy Great Robots Fail as Businesses, and What iRobot Got RightModeration: Lex FridmaniRobot co-founder Colin Angle explains why so many robotics companies collapse and how cost, vision and a clear user need shaped the Roomba.
1:35:38ENInside ChatGPT: How a Hackathon Project Became the World's Most Used AI ProductGast: Nick Turley · Moderation: Lenny RachitskyNick Turley, head of ChatGPT at OpenAI, explains how the product was built, why shipping fast beats polishing first, and where it goes next.
1:04:25ENInside GitHub's Copilot Bet: Agents, Open Source, and Why the Developer Job EnduresModeration: Jacob EffronGitHub CEO Thomas explains how Copilot went from a research bet to 1.3 million developers, and what agents, fine-tuning and a multi-model world mean for the next five years of software.
1:11:56ENHow to Get ChatGPT to Recommend Your Product: A Practical Guide to Answer Engine OptimizationGast: Ethan Smith · Moderation: Lenny RachitskyGraphite CEO Ethan Smith explains how AEO differs from SEO, which levers move the needle, and how to measure and test what works.
1:19:13ENAlien Intelligence, Radical Upside: Nathan Labenz on Why AI Is the Next Industrial RevolutionModeration: Nathan LabenzIn the second episode of The Cognitive Revolution, Nathan Labenz tells Erik Torenberg how he went from asteroid-watching AI skeptic to full-time AI scout, and lays out the upside and downside cases.
18:46ENDeep Learning Plus One Idea: Ilya Sutskever on Building AGIModeration: Lex FridmanIn a May 2020 conversation, Sutskever discusses self-play, simulation, bodies and consciousness, tests of intelligence, and how an AGI might be governed and aligned.
1:05:39ENThe Positioning Fix: Why Great B2B Products Still Need a Story Buyers Can RepeatModeration: Lenny RachitskyApril Dunford explains how to diagnose weak positioning, build differentiated value, and turn it into a sales narrative that wins B2B deals.
1:23:15ENCamille Fournier on Rewrites, One-on-Ones and Building Platform TeamsGast: Camille Fournier · Moderation: Lenny RachitskyThe author of The Manager's Path explains what annoys engineers about PMs, why rewrites are a trap, how to move into management, and what makes platform teams work.
22:59ENPenrose on Why Consciousness Can't Be a ComputationModeration: Lex FridmanRoger Penrose explains how a dissatisfaction with AI optimism, a tip about microtubules and a rethink of quantum mechanics led him to Orch OR.
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