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22:17ENWhat Is Real? Lee Smolin on Realism, Science and StorytellingModeration: Lex FridmanThe theoretical physicist explains why he believes in a world independent of our perception, why he doubts there is a single scientific method, and where realism meets quantum mechanics.
1:27:51ENOptimism, Laziness and "What If": Lessons from the Man Behind Google DocsGast: Sam Schillace · Moderation: Lenny RachitskySam Schillace, who created Writely (later Google Docs) and now helps lead AI work at Microsoft, on disruptive ideas, user laziness, failing on purpose, and where software is headed.
1:12:18ENThe Lego Inside Notion: Ivan Zhao on Lost Years, Small Teams, and Horizontal BetsModeration: Lenny RachitskyIvan Zhao explains how Notion survived its lost years, stayed lean, corrected a non-Lego product detour, and built a horizontal platform now being reshaped by AI.
1:35:10ENTen Growth Tactics That Never Work, According to Elena VernaGast: Elena Verna · Moderation: Lenny RachitskyGrowth leader Elena Verna runs through the growth plays she sees companies waste money on, the three frameworks she trusts instead, and her case for career optionality.
1:42:11ENTwenty Agents, 1.2 Humans: Inside SaaStr's AI-Run Sales TeamModeration: Lenny RachitskyJason Lemkin explains how SaaStr replaced a ten-person go-to-market team with AI agents, what it took to train them, and who survives the shift.
1:09:38ENRyan Hoover on Experiments, Launches and the Mask Every Founder WearsGast: Ryan Hoover · Moderation: Lenny RachitskyThe Product Hunt founder and Weekend Fund investor talks about starting small, raising money for a reason, launching well, his own regrets and how he now invests.
1:22:51ENCold DMs, Dinner-Party Communities, and the Case Against Jobs-to-Be-DoneModeration: Lenny RachitskyAarthi Ramamurthy and Sriram Krishnan on techno-optimism, relationship-driven careers, content creation, imposter syndrome, executive reviews, and why real products are trade-offs.
1:01:13ENNLX Is the New UX: Microsoft's Aparna Chennapragada on Designing for AgentsGast: Aparna Chennapragada · Moderation: Lenny RachitskyMicrosoft's chief product officer explains how she is building AI products a year ahead of the market, why conversation is a designable interface, and what stays the same for product builders.
15:43ENInside RIDER: The Rugged Black Box Behind MIT's Large-Scale Driving StudyGast: MIT-AVT · Moderation: Lex FridmanA walkthrough of the data-collection device MIT-AVT uses to record drivers and vehicles in semi-autonomous cars month after month.
1:02:51ENThe Unreasonable Playbook Behind Gojek: Super Apps, Cash Vaults, and Brand as a MoatModeration: Lenny RachitskyKevin Aluwi explains how Gojek scaled across Southeast Asia by building brand, running brutal operations, and rejecting copycat strategy.
56:42ENInside Gong's Product Machine: Pods, Design Partners, and Fast 51/49 DecisionsModeration: Lenny RachitskyEilon Reshef explains how Gong pairs autonomous product pods with design partners, makes quick decisions, and builds AI products with measurement and expertise.
37:18ENFrom Intelligent Copilots to Aurora: Sterling Anderson on Shared Control and Building a Self-Driving CompanyModeration: Lex FridmanA guest lecture in MIT's 6.S094 course tracing Anderson's path from shared human-machine control research, through Tesla Autopilot, to co-founding Aurora.
1:06:53ENLenny Rachitsky Answers Questions From His Wife: How a Newsletter Nobody Planned Became a BusinessModeration: Lenny RachitskyIn a role-reversal episode, author Michelle Rial interviews Lenny about the moments that led to his newsletter, the stress behind the scenes, and what he has learned about quality and iteration.
1:02:33ENEmpathy, Half-Built Products and Staying Power: Scott Belsky on Product Sense in the Age of AIGast: Scott Belsky · Moderation: Lenny RachitskyAdobe's chief strategy officer explains how he builds product intuition, why he kills features, how AI could change creative work, and when a founder should quit.
1:50:55ENTwo Hierarchies for Consumer and Marketplace Startups: Focus First, Tip Second, Dominate LastGast: Sarah Tavel · Moderation: Lenny RachitskyBenchmark partner Sarah Tavel walks through her hierarchy of engagement and hierarchy of marketplaces, and why both start with ruthless focus.
44:53ENLegora's CEO on Building Legal AI That Survives the Next Model ReleaseModeration: Jacob EffronMax explains how Legora turns fast-moving model capabilities into end-to-end legal work, enterprise adoption, and a durable product strategy.
1:40:42ENThe IC CEO: How Airtable's Howie Liu Is Re-Founding a 13-Year-Old Product for AIGast: Howie Liu · Moderation: Lenny RachitskyAirtable's co-founder explains why he returned to hands-on product work, split his org into fast- and slow-thinking groups, and what skills every product team now needs.
21:48ENDon't Build Zombie UI: Katie Dill on Scaling Intent and Craft in the AI Building BoomModeration: Lenny RachitskyStripe's head of design argues that as AI lets everyone build, a clear point of view, encoded standards, ruthless editing and real creative ambition are what keep products from turning generic.
17:11ENDisagreement as an Art: How Lex Fridman Handles Negative CommentsModeration: Lex FridmanIn an AMA answer, Lex Fridman explains how he separates respectful disagreement from mockery and how he turns the sting of criticism into a lesson.
1:45:10ENShape Up in Real Life: Fixed Time, Variable Scope, and the Shaping Session That Makes It WorkGast: Ryan Singer · Moderation: Lenny RachitskyRyan Singer, author of Shape Up, explains appetites, six-week time boxes and live shaping sessions, and why copying Basecamp's method without its conditions fails.
2:14:39ENBrains at Work: A Neuroscience Playbook for Meetings, Influence and Team CultureGast: Evan LaPointe · Moderation: Lenny RachitskyCORE Sciences founder Evan LaPointe turns the brain's safety, reward and purpose systems into practical advice for meetings, relationships, culture and focus.
1:21:08ENThe Magic Loop: How a Former Amazon VP Says You Can Earn Promotions by Helping Your BossGast: Ethan Evans · Moderation: Lenny RachitskyEthan Evans explains his five-step career loop, how to break through at senior manager, how to invent on purpose, and what he learned from failing Jeff Bezos on a very public launch.
1:39:10ENAfter the Keyboard: Why Physical AI Is the Next Frontier, According to a Veteran Hardware LeaderModeration: Lenny RachitskyCaitlin Kalinowski, who has built products at Apple, Meta and OpenAI, explains why robotics is heating up, what actually gates it, and how to build hardware that ships.
1:20:58ENFrom Bag of Words to Attention: Quoc Le Teaches Sequence-to-Sequence Learning Through Email RepliesModeration: Lex FridmanA Deep Learning School talk that builds sequence-to-sequence models step by step around one running example, automatic email reply, and then surveys memory and operation-augmented networks.
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