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45:00ENAgents Everywhere: OpenAI's Blueprint for Tool Use, Evals, and Computer-Use InfrastructureModeration: Jacob EffronOpenAI's API platform team explains how agents are moving from deterministic workflows to reasoning-driven tool use, and what developers still lack.
1:31:56ENPerfect Is Creepy: What a Child Psychologist Knows About Leading Difficult AdultsModeration: Lenny RachitskyDr. Becky Kennedy explains how the principles she uses to raise resilient kids apply to managers, teams and colleagues.
1:04:06ENBuild the Model, Then Garden the Marketplace: Dan Hockenmaier on Growth Models and Marketplace StrategyGast: Dan Hockenmaier · Moderation: Lenny RachitskyFaire's head of strategy and analytics explains how to build a growth model, which marketplace metrics matter, and why marketplaces demand a light touch.
54:52ENCoding Agents Are Breaking Containment: The 2026 AI Stack, the Coding Wars, and the Next FrontierModeration: Jacob EffronJacob Effron and Swyx map the state of AI engineering, from agent harnesses and infrastructure churn to coding-market economics, open models, dark factories, and world models.
1:28:38ENBuild for Feelings, Not Graphs: Inside The Browser Company's Product PhilosophyGast: Josh Miller · Moderation: Lenny RachitskyJosh Miller, CEO of The Browser Company, explains how Arc is built around emotions, values, a tiny-but-unusual team and a bet on the internet as the next computer.
10:39ENStatistics as Decision-Making: Michael I. Jordan on Bayesians, Frequentists and the Ideas Between ThemModeration: Lex FridmanBerkeley's Michael I. Jordan explains where statistics came from, why it is really about decisions, and how empirical Bayes and false discovery rate bridge two rival philosophies.
11:29ENWhy Tesla AI Day Was the Most Impressive Real-World AI Effort Lex Fridman Has SeenModeration: Lex FridmanLex Fridman walks through the neural network, data annotation, Dojo and Tesla Bot announcements and what they say about solving real-world robotics.
1:38:33ENPrice Before Product: Madhavan Ramanujam's Masterclass on Monetizing InnovationGast: Madhavan Ramanujam · Moderation: Lenny RachitskyThe author of Monetizing Innovation walks product teams through willingness-to-pay research, segmentation, pricing models, benefit messaging and behavioral pricing.
1:06:22ENPerplexity's Bet: Search Becomes Answers, and Answers Become a BusinessModeration: Jacob EffronThe Perplexity CEO explains how a consumer AI search product is built, sequenced, and defended against Google.
1:01:12ENThe Failure Dividend: What Leaders from Airbnb, Google, Pets.com, Quibi, Duolingo, and Toast Learned from Their Worst MomentsModeration: Lenny RachitskyA compilation of product leaders' most searing failures—and the operating lessons they extracted from them.
52:28ENRay Kurzweil on Hierarchies, the Neocortex and Merging with AIGast: Ray Kurzweil · Moderation: Lex FridmanIn an MIT AGI course lecture, Kurzweil connects the history of neural networks to his hierarchical theory of the neocortex, language understanding at Google, longevity, jobs and existential risk.
1:19:32ENProduct Ops Is the Operating System Your Product Team Is MissingModeration: Lenny RachitskyMelissa Perri and Denise Tilles explain how product operations frees product managers from busywork, improves decision speed, and scales product organizations without adding unnecessary overhead.
48:18ENStop Writing Solutions as Opportunities: Teresa Torres on Opportunity Solution Trees and Weekly Customer InterviewsGast: Teresa Torres · Moderation: Lenny RachitskyThe author of Continuous Discovery Habits explains how to structure a messy product problem, collect customer stories every week, and make better bets with small amounts of data.
2:03:00ENBan Superintelligence or Build the Rules as We Go? Max Tegmark and Dean Ball Clash Over a Precautionary AI RegimeModeration: Nathan LabenzIn a Doom Debates crossover, the Future of Life Institute's Max Tegmark and former White House adviser Dean Ball argue over whether superintelligence should be prohibited until it is provably controllable.
1:25:15ENProduct Management Theater and the Road Out: Marty Cagan on TRANSFORMEDGast: Marty Cagan · Moderation: Lenny RachitskyThe SVPG founder explains why many PM roles are really project management, how AI raises the stakes, and how companies can move from feature teams to empowered product teams.
1:00:15ENCircuit Search, Hindsight and Self-Play: Ilya Sutskever's Case for Where Learning Is GoingGast: Ilya Sutskever · Moderation: Lex FridmanIn an MIT AGI lecture, OpenAI's co-founder explains why deep learning works, then walks through meta-learning, hindsight experience replay, sim-to-real transfer, self-play and learning goals from human feedback.
1:36:53ENIdeology, Restraint and the Core: Peter Sellis on Building Product Teams That WinModeration: Lenny RachitskySnapchat's first PM and former Discord head of product speaks candidly about team design, why the median PM is weak, and where consumer growth really comes from.
1:16:05ENThe Founder Is the Product: A Tactical Guide to Founder-Led SalesModeration: Lenny RachitskyJen Abel walks through outbound messaging, first calls, co-authored scoping, procurement, and closing for early-stage founders.
20:16ENProduct Management Is Dead. What Comes Next Is an AI-Powered Triple ThreatModeration: Lenny RachitskyClaire argues that AI is collapsing the PM craft and replacing the product triad with multi-skilled leaders backed by agents, tools and a culture of automation.
1:46:04ENWhy Growth Stalls: Jason Cohen's Ordered Checklist for Getting UnstuckGast: Jason Cohen · Moderation: Lenny RachitskySerial founder Jason Cohen walks through the questions he asks, in order, when a product's growth slows, from churn and pricing to net revenue retention, saturated channels and whether you need to grow at all.
18:24ENFive Lessons from a 91-Year-Old Grandmother: Lex Fridman Remembers the Woman Who Shaped HimModeration: Lex FridmanLex Fridman uses his microphone to honor his late grandmother, recounting what she taught him about toughness, strength, quiet thought, self-belief and love.
11:26ENThe Cookie Your Brain Bakes: Joscha Bach on Happiness, Cells and the Meaning of GodModeration: Lex FridmanIn a short clip, Joscha Bach moves from why happiness is not the point to the cell as a cosmic probe and a naturalistic reading of God as civilization.
2:02:13ENWiring Without a Vision: What OpenAI's and Google's Dueling Launches Really SignalModeration: Nathan LabenzZvi Mowshowitz and Nathan Labenz unpack the week of GPT-4o and Google I/O, from rushed demos and AI companions to the big tech singularity and the exodus from OpenAI's safety team.
1:47:58ENBridging the Divide: How Community Notes Built a Trusted Fact-Checking System on DisagreementGast: Keith Coleman, Jay Baxter · Moderation: Lenny RachitskyKeith Coleman and Jay Baxter, the team behind Community Notes, explain how the algorithm works, how a tiny team built it, and why it survived four leaders at Twitter and X.
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