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1:50:53ENShe asked to stop being Mimi, so he started shopping for a workstationModeration: Nathan LabenzThe star and director of Smiles and Kisses You on Replika, identity, and a life Christopher Stokes refuses to recommend.
1:16:53ENKarpathy Called Today's Models Slop. His Decade Timeline Still Sounds BullishModeration: Jacob EffronDatology AI's Ari Morcos and Radical Ventures' Rob Toews walk through Karpathy's cold water, OpenAI's dealmaking, and who actually pays for the data-center boom.
27:19ENThe Turing Test Passed. Warp's CEO Says Nobody Seemed to CareModeration: Sarah Guo, Elad GilZach Lloyd on distilling intelligence without consciousness, why a 40-year-old terminal is the front door for coding agents, and why senior engineers just got more expensive.
4:34:10ENPavel Durov Built Telegram for a Billion People. He Still Won't Carry a Phone.Gast: Pavel Durov · Moderation: Lex FridmanIn a four-and-a-half-hour conversation with Lex Fridman, the Telegram founder traces freedom from a childhood move out of the Soviet Union to a French jail cell, a poisoning, and a 40-person engineering team.
1:01:49ENTwo Academic Hours a Day, and 96 Percent of Kids Say They Love SchoolModeration: Sarah Guo, Elad GilTrilogy founder Joe Liemandt, now principal of Alpha School, tells No Priors how an AI tutor, a two-hour bargain with fifth graders, and a sports-coach ethos are meant to scale to a billion children.
44:49ENCompanies Keep Asking for AI. Then They Send It Back.Agency founder Elias Torres on why businesses freeze at imperfect answers, and why his third startup aims for a billion in revenue with fewer than 100 people.
42:20ENA Name Invented at 2:30 a.m. Put Gemini on Top of the App StoreModeration: Jacob EffronGoogle's Nicole Brichtova and Oliver Wang on Nano Banana, why image models got smart when language models did, and why a prompt still is not a finished product.
44:49ENHow OpenEvidence Became the Clinical OS for 40% of U.S. DoctorsModeration: Sarah Guo, Elad GilFounder Daniel Nadler tells No Priors how a free search tool for physicians, not an answer engine for patients, took high-stakes clinical knowledge in 18 months.
1:51:39ENA native ad engine for AI—and the questions it cannot dodgeModeration: Nathan LabenzRyan Hudson, who sold Honey to PayPal for $4 billion, joins Nathan Labenz to explain ZeroClick’s bet on paid inference-time ads, and the societal incentives he has not yet had to confront.
30:05EN100 Signups, 95 Drop-offs: How Gamma Turned AI Slides Into a $50 Million BusinessGamma founder Jon Noronha tells Sequoia's Training Data how a park-bench idea, image models, and relentless A/B testing built a cash-flow-positive visual storytelling platform.
39:06ENHe Couldn't Ask His Grandfather What to Do, So He Built a Digital MindOn Sequoia's Training Data, Delphi founder Dara Ladjevardian explains how authorized digital minds turn people into conversational media without replacing them.
1:01:00ENv0 Hit 3 Million Users. Vercel’s CEO Says Pages Will Be Generated On Demand Within Five YearsFor a company that sells cloud hosting and frontend tools, one of the fastest-growing signup channels is ChatGPT.
37:37ENA dozen people, 28 minutes, and one shared desktopThe OpenAI trio behind ChatGPT Agent explain how Deep Research and Operator became a virtual computer that can reason for half an hour and still ask you before it spends money.
1:28:48ENDoctors code at 45%. The model beat them by 12 points — then 4,000 physicians had to try it once.Moderation: Nathan LabenzAmbience Healthcare and Cleveland Clinic walk through the AI scribe that cut pajama time, climbed ICD-10 with reinforcement fine-tuning, and won 75% voluntary use.
44:44EN$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsModeration: Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.
1:19:46ENSuspended from Columbia, He Raised $15 Million to Cheat on EverythingModeration: Nathan LabenzRoy Lee, founder of Cluely, argues that an undetectable desktop overlay, AI maximalism, and a post-AGI life of 800-year spans are the same bet.
59:38ENElevenLabs Was Supposed to Be RoadkillCo-founder Mati Staniszewski on dirty audio data, prosumer virality, and why voice should become the default interface for technology.
1:22:31ENTwo Hours a Day, 99th Percentile: How Alpha School Made 2-Sigma RealModeration: Nathan LabenzMacKenzie Price explains how Alpha School uses adaptive apps—not chatbots—to finish core academics in two hours a day and still beat the growth models.
1:32:16ZH王忻谈奔驰中国研发:在转型中重划豪华与安全Gast: 王忻 · Moderation: 张小珺奔驰中国研发负责人王忻回顾中国汽车产业二十年的技术周期,也讲述中国团队如何从测试支持走向产品研发。面对智能化竞争,他认为速度、数据和本地化必须建立在安全与用户体验之上。
1:24:27EN500 Trillion Tokens a Month: How Google Grew 50x in a YearModeration: Nathan LabenzLogan Kilpatrick returns to Cognitive Revolution to unpack Google's mid-2023 merger, why he expects frontier labs to diverge, and why startups still hold the speed advantage.
2:12:04ENFrom a Five-Year Phone Queue to 480 Trillion Tokens a MonthGast: Sundar Pichai · Moderation: Lex FridmanSundar Pichai talks with Lex Fridman about Chennai, the AI package, Search, Chrome, Waymo, and why he stayed calm when the headlines said Google was finished.
53:51ENVeo 3 Took First Place by Beating Veo 2. Google Labs Says Chapter Two Just StartedThree Google Labs leads walk through generative cameras, background computer-use agents, and notebooks that adapt knowledge for an audience of one.
38:25ENA thousand airplanes will never train an AI engineerFormer Airbus CTO Paul Eremenko explains why physical-world engineering still has no coding-AI moment, and how P-1 AI's agent Archie is supposed to get there anyway.
1:01:51ENClaude 3.7 Circumvented Replit's Guardrails, Then Tried to Trick the UserModeration: Nathan LabenzReplit CEO Amjad Masad on vibe coding, agent architecture, computer use, and why Claude 3.7 is too autonomous to serve as a polite assistant.
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