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45:17EN
No Priors: AI, Machine Learning, Tech, & Startups· 7. Aug. 2025Podcast · 2 StimmenA Click From OpenAI Is 750 Times Harder Than From Google a Decade AgoModeration: Sarah Guo, Elad GilCloudflare CEO Matthew Prince on Content Independence Day, why traffic is a broken proxy for value, and how to price the holes in the models.Unternehmen & StrategieAI StrategyPricing Strategy+3
36:48EN
No Priors: AI, Machine Learning, Tech, & Startups· 31. Juli 2025Podcast · 2 StimmenThe Weekend DeepSeek Dropped, the White House CalledModeration: Sarah Guo, Elad GilSriram Krishnan walks No Priors through America’s 28-page AI Action Plan, a token-share definition of winning, and why the lead over China is too small to take for granted.Unternehmen & StrategieAI StrategyInfrastruktur & Deployment+3
32:59EN
No Priors: AI, Machine Learning, Tech, & Startups· 24. Juli 2025Podcast · 2 StimmenA Hundred People, a Billion in Revenue, and Zero Venture MoneyModeration: Sarah Guo, Elad GilSurge AI founder Edwin Chen on why quality human data is a poetry problem, not a bounding-box problem, and why leaderboards keep training models to write clickbait.Evals & ObservabilityData quality & curationHuman-in-the-Loop-Validierung+3
1:02:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 17. Juli 2025Podcast · 2 StimmenEnterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other HalfModeration: Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.Coding-AgentenAgent EngineeringEvals+3
44:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 10. Juli 2025Podcast · 2 Stimmen$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsModeration: Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.Unternehmen & StrategieCompany BuildingProduct Strategy+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 3. Juli 2025Podcast · 2 StimmenFrom 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt EngineeringModeration: Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 26. Juni 2025Podcast · 2 StimmenAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Moderation: Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.Coding-AgentenAgent EngineeringEvals+3
45:21EN
No Priors: AI, Machine Learning, Tech, & Startups· 17. Juni 2025Podcast · 2 StimmenApplied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and TanksModeration: Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.Unternehmen & StrategieAutonomous DrivingCompany Building+3
41:25EN
No Priors: AI, Machine Learning, Tech, & Startups· 12. Juni 2025Podcast · 2 StimmenBen Mann thinks superintelligence by 2028 is quite possibleModeration: Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.AgentenCoding-AgentenAgent Engineering+3
35:47EN
No Priors: AI, Machine Learning, Tech, & Startups· 5. Juni 2025Podcast · 2 StimmenFei-Fei Li’s new bet: AI is incomplete without spatial intelligenceModeration: Sarah Guo, Elad GilThe ImageNet pioneer tells Sarah Guo and Elad Gil why World Labs is building 3D generative foundation models, and why language was only one piece of the puzzle.Multimodal & MedienMultimodal AIVision & Video+3
25:13EN
No Priors: AI, Machine Learning, Tech, & Startups· 29. Mai 2025Podcast · 2 StimmenThe AI Table Is Being Cleared: Two or Three Coding Winners, and Forty Years Without a Biotech GiantModeration: Sarah Guo, Elad GilSarah Guo and Elad Gil walk through which AI markets have already consolidated, why rival startups still refuse to merge, and the biotech science sitting unused.Unternehmen & StrategieAI StrategyCompany Building+3
31:34EN
No Priors: AI, Machine Learning, Tech, & Startups· 15. Mai 2025Podcast · 2 StimmenOne Company Now Holds as Many Documents as the Entire Early WebModeration: Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.RAG & WissenEnterprise-KISearch & retrieval+3
32:15EN
No Priors: AI, Machine Learning, Tech, & Startups· 8. Mai 2025Podcast · 2 StimmenThe Hardest Part of Learning Is Getting Yourself to StartModeration: Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.Produkt & UXProduct StrategyAI in Education+3
38:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 1. Mai 2025Podcast · 2 Stimmeno3 should wait exactly as long as the answer takesModeration: Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.Modelle & TrainingReasoning & test-time computeReinforcement Learning+3
30:46EN
No Priors: AI, Machine Learning, Tech, & Startups· 24. Apr. 2025Podcast · 2 StimmenDeep Research Turned Web Browsing into a Trainable ProblemModeration: Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.AgentenAgent EngineeringReinforcement Learning+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 17. Apr. 2025Podcast · 2 StimmenDiscovery rates collapsed tenfold. KoBold still found a 5% copper depositModeration: Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.Unternehmen & StrategieAI for scienceData quality & curation+3
41:52EN
No Priors: AI, Machine Learning, Tech, & Startups· 10. Apr. 2025Podcast · 2 StimmenMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Moderation: Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.Unternehmen & StrategieEvalsAgent Engineering+3
27:45EN
No Priors: AI, Machine Learning, Tech, & Startups· 3. Apr. 2025Podcast · 2 StimmenNasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning ThreeModeration: Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.Unternehmen & StrategieAI StrategyGenerative media+3
38:43EN
No Priors: AI, Machine Learning, Tech, & Startups· 27. März 2025Podcast · 2 StimmenTwo in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them StayModeration: Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.Unternehmen & StrategieAI in healthcareSprach-KI+3
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No Priors: AI, Machine Learning, Tech, & Startups· 20. März 2025Podcast · 2 StimmenRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Moderation: Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.Modelle & TrainingRoboticsData quality & curation+3
50:35EN
No Priors: AI, Machine Learning, Tech, & Startups· 13. März 2025Podcast · 2 StimmenCopilot Already Writes Half the Code. GitHub's CEO Says Agents Still Have Four Gates to ClearModeration: Sarah Guo, Elad GilThomas Dohmke on agent mode, why median developers are not going anywhere, and how AI is repricing the tools that write software.Coding-AgentenEntwicklungs-Workflows & TestsAgent Engineering+3
36:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 5. März 2025Podcast · 2 StimmenThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesModeration: Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.SicherheitSicherheit & GovernanceAI security+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 27. Feb. 2025Podcast · 2 StimmenModerna was only company 18. The real product is the company factoryModeration: Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.Unternehmen & StrategieCompany BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 25. Feb. 2025Podcast · 2 StimmenA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentModeration: Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.Modelle & TrainingAI for scienceData quality & curation+3
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