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1:05ENSatya Nadella on AI, Productivity, and Cancer CareMatthew Berman, Satya Nadella · Forward FutureIn a short interview excerpt, the Microsoft CEO discusses the potential of cheaper AI to help coordinate healthcare work.
1:19:40ENIan Henry on Building Trader Tools, Functional UIs and Creative CodingYaron Minsky, Ian Henry · Jane StreetFrom high-density options interfaces to a 3D playground, Ian Henry and Ron Minsky explore the software choices that make complex tools usable.
1:35:12ENJack Zhang on Building Airwallex and Scaling Global PaymentsGast: Jack Zhang · Moderation: Harry StebbingsThe Airwallex founder recounts early funding, product pivots, a proposed Stripe deal and the costs of international expansion.
3:24:36ENA tank man came home and could not stayGast: James Holland · Moderation: Lex FridmanHistorian James Holland tells Lex Fridman why World War II was an ideological war of factories, letters, and logistics — and why Germany could not win it.
2:19:08ENOliver Anthony sang the pain of working America, then refused the machineGast: Oliver Anthony · Moderation: Lex FridmanLex Fridman sits with the Virginia singer-songwriter whose carport hit became a working-class anthem, and who still treats fame as a test of integrity rather than a prize.
1:56:42ENDuolingo’s Severin Hacker on AI Tutors, Learning and Building a CompanyGast: Severin Hacker · Moderation: Harry StebbingsThe co-founder explains how Duolingo uses AI, where he sees limits in current tools and why his forecasts about education and work remain uncertain.
31:34ENOne Company Now Holds as Many Documents as the Entire Early WebModeration: Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.
1:04:29ENImmad Akhund on Mercury, Angel Investing and His New FundGast: Immad Akhund · Moderation: Harry StebbingsThe Mercury CEO discusses a $26 million institutional fund, early-stage investing, AI valuations and the demands of running both.
32:15ENThe Hardest Part of Learning Is Getting Yourself to StartModeration: Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.
1:03:27ENBucky Moore on Venture Platforms, AI and Early-Stage InvestingGast: Bucky Moore · Moderation: Harry StebbingsThe new Lightspeed partner discusses capital-intensive model companies, seed valuations, founder selection and the role of large venture firms.
3:00:50ENA Black Hole Is a Place, Not a ThingGast: Janna Levin · Moderation: Lex FridmanTheoretical physicist Janna Levin tells Lex Fridman why the event horizon is empty spacetime, why Hawking’s radiation started a war over information, and why gravity itself may not be fundamental.
38:10ENo3 should wait exactly as long as the answer takesModeration: Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.
4:25:19ENA shareware text editor, a 30-hour binge, and a five-year war with AppleGast: Tim Sweeney · Moderation: Lex FridmanTim Sweeney traces Unreal Engine’s thirty-year climb, the four-week birth of Fortnite Battle Royale, a new language for the metaverse, and why he thinks Apple is on the wrong side of computing history.
1:02:51ENTaavet Hinrikus on Venture Incentives and Europe’s Technology AmbitionsGast: Taavet Hinrikus · Moderation: Harry StebbingsThe Wise co-founder and Plural partner explains his approach to early-stage investing, fund alignment and building European capabilities.
30:46ENDeep Research Turned Web Browsing into a Trainable ProblemModeration: Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.
3:04:01ENXi Jinping Revived China's Personality Cult. He Did Not Revive Mao's Chaos.Gast: Jeffrey Wasserstrom · Moderation: Lex FridmanHistorian Jeffrey Wasserstrom on Confucius, Tiananmen, censorship, the 2025 trade war, Hong Kong's warning to Taiwan, and why history has no straight road.
1:01:21ENJason Wilk on Dave’s Turnaround, Credit and Digital BankingGast: Jason Wilk · Moderation: Harry StebbingsThe Dave founder discusses going public, AI underwriting, customer acquisition and competing to serve consumers with short-term credit.
3:29:02ENRobert Rodriguez: Sift the Ashes, Keep the Pipe Open, Don't BlinkGast: Robert Rodriguez · Moderation: Lex FridmanThe director of El Mariachi, Desperado, Sin City, and Alita: Battle Angel tells Lex Fridman how limitation, failure, sound, and identity became his method.
40:54ENDiscovery rates collapsed tenfold. KoBold still found a 5% copper depositModeration: Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.
1:12:26ENVictor Lazarte on Founders, AI and Investing Through a Technology ShiftGast: Victor Lazarte · Moderation: Harry StebbingsThe Benchmark partner discusses founder selection, AI revenue quality, the future of work and the role of a venture investor.
41:52ENMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Moderation: Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.
3:19:00ENTen Minus Two Equals TwentyGast: Dave Smith · Moderation: Lex FridmanComedian and libertarian Dave Smith tells Lex Fridman that American wars keep manufacturing enemies, that Gaza and Ukraine follow the same arithmetic, and that long conversations broke the old monopoly on selling war.
1:10:19ENCarvana CEO Ernie Garcia on Conviction, Debt and Building Through Difficult MarketsGast: Ernest Garcia · Moderation: Harry StebbingsThe co-founder reflects on fundraising, operations, public markets and the personal trade-offs of leading a company.
27:45ENNasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning ThreeModeration: Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.
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