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1:44:23ENYou Can Split Your Vote by Issue — and Hand It to an AIModeration: Nathan LabenzTim Reutemann’s 2018 novel Liquid Reign sketches a 2051 democracy built on Swiss citizen initiatives, liquid delegation, and personal AIs you can mute.
1:01:53ENCompanion Apps Open Twice as Often as TikTok. a16z Only Funds Weird but WorkingModeration: Nathan Labenza16z consumer partners Anish Acharya and Justine Moore walk Nathan Labenz through their Abundance Agenda for AI-native consumer apps.
1:15:39ENAfter 20 Years of Frontend, v0 Wrote Better Code Than Guillermo Rauch DidModeration: Nathan LabenzThe Vercel CEO tells Nathan Labenz why every product needs ghost text, why Software 2.0 will ossify the old stack, and why betting against open source is still the expensive mistake.
1:25:11EN105 lines of code, a million impressions, and a VC who refused to found the companyModeration: Nathan LabenzBabyAGI creator Yohei Nakajima tells Nathan Labenz how a weekend prototype set off the agent wave — and why he went back to writing checks.
55:13ENTwo Days to a Prototype: How a16z Turned a Stanford Paper Into AI TownModeration: Nathan LabenzA companion named Alice, a weekend Phaser hack, and Martin Casado's argument that models will never replace formal languages.
1:01:09ENHugging Face Raised $235M. Community Still Is Not a MoatModeration: Nathan LabenzNathan Labenz and Erik Torenberg unpack Hugging Face's $4.5 billion Series D, and why a thriving open-source hub may still struggle to become a locked-in business.
1:39:53ENUnder 100 People, 24 Million Users: Replit's Bet on Artificial Developer IntelligenceModeration: Nathan LabenzMichele Catasta, Replit's new VP of AI, lays out a generate-execute-learn loop he will not call AGI, a 2x-to-1000x productivity ladder, and a keystroke-level data advantage.
1:32:22ENA Million Bytes and 256 Symbols: Meta's MEGABYTE Wants to Throw the Tokenizer AwayModeration: Nathan LabenzLili Yu of Meta AI explains a multiscale transformer that predicts million-byte sequences, skips tokenization, and aims to model any file as raw bytes.
1:26:20ENForty Dollars to Index Joe Rogan: Chroma, Shovels, and the Wright Flyer Era of MLModeration: Nathan LabenzChroma co-founder Anton Troynikov on embeddings as the storage layer for language-model apps, Stable Attribution, and why machine learning is still flying on intuition.
2:54:52ENThe Marvelous Proof Still Lives in the MarginModeration: Lex FridmanLuís and João Batalha, the brothers behind Fermat's Library, talk with Lex Fridman about hidden backstories, a publishing system that buys its own work twice, and how to sit with a paper until it finally clicks.
17:19ENMoney Is a Game of Points: Vitalik Buterin on Coordination, Public Goods, and Quadratic FundingModeration: Lex FridmanVitalik Buterin explains money as a social point system, why value can survive without physical backing, and how quadratic funding tries to fix public-good underfunding.
1:13:51ENAnswering Questions Without Seeing the Data: Andrew Trask on the Privacy-Preserving AI StackModeration: Lex FridmanA tour of remote execution, differential privacy, secure multiparty computation, and the societal consequences of making private data usable.
1:06:39ENWhy Jane Street Uses OCamlA Jane Street talk explains how functional programming and static types support reliable trading software, and examines the costs of choosing a less common language.
1:05:22ENBuild First, Optimize Later: Harrison Chase on LangChain, Evals, and the State-Machine Future of AgentsModeration: Jacob EffronHarrison Chase explains how LangChain grew from an orchestration layer into LangSmith and LangGraph, why evaluation datasets force product clarity, and why reliable agents look more like state machines than autonomous loops.
1:11:06ENReplit's Amjad Masad on Building Your Own Model, Latency, and the Next Billion Software CreatorsModeration: Jacob EffronThe Replit founder explains why AI should be native to the product, why he trained a small in-house model, and why he thinks software engineering is about to split in two.
40:00ENThe Winds of Change: How Mistral Plans to Win the Open-Model EraModeration: Jacob EffronArthur Mensch explains Mistral's open-source strategy, enterprise distribution, model research, and views on AI regulation and sovereignty.
1:12:15ENThe Open-Model Vibe Check: China, Containment, and the Data MoatModeration: Jacob EffronJacob Effron and guests debate Chinese open-weight models, distillation, containment policy, the OpenAI–Hugging Face incident, and Cursor's data advantage.
1:03:25ENTheano in an Hour: Symbolic Graphs, Automatic Gradients and a Compiler That Rewrites Your MathModeration: Lex FridmanPascal Lamblin of MILA walks through how Theano builds, differentiates, optimizes and runs computation graphs, then trains logistic regression, a convnet and an LSTM.
50:23ENOpenAI’s Platform Bet: Where AI Value Accrues, Why Open Source Trails, and When Superintelligence ArrivesModeration: Jacob EffronPeter Welinder explains OpenAI’s platform strategy, the case for proprietary frontier models over open source, the enterprise hallucination problem, and his speculative timeline for AGI and superintelligence.
1:02:06ENLearning TensorFlow Hands-On: From a Mystery Line to Handwritten DigitsModeration: Lex FridmanGoogle Brain's Sherry Moore walks a Deep Learning School audience through how TensorFlow works and two core labs, linear regression and MNIST digit recognition.







