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4:25:13ENThe Architecture Barely Changed. Data, Cost, and Open Weights Did.Moderation: Lex FridmanNathan Lambert and Sebastian Raschka walk Lex Fridman through a year in which training methods and datasets moved more than model design, and 2026 looks like a fight over inference cost, agents, and who owns truly open models.
5:15:00ENDario Amodei Has Seen This Scaling Movie Enough TimesGast: Dario Amodei · Moderation: Lex FridmanAnthropic’s CEO puts numbers on frontier training costs and AGI, then hands the mic to the people who shape Claude’s character and look inside its weights.
2:47:17ENIf You Want Human-Level AI, Abandon Generative ModelsGast: Yann Lecun · Moderation: Lex FridmanYann LeCun tells Lex Fridman why autoregressive LLMs cannot plan, remember, or understand the physical world — and why open source is the only democratic answer.
4:14:33ENThe Next Token Is Not a Proof: Stephen Wolfram on ChatGPT and Computational TruthGast: Stephen Wolfram · Moderation: Lex FridmanIn his fourth conversation with Lex Fridman, Stephen Wolfram contrasts large language models with Wolfram|Alpha, then follows computational irreducibility from ChatGPT through observers, thermodynamics, and the three great theories of twentieth-century physics.
3:28:47ENKarpathy Calls Trained Neural Nets Complicated Alien ArtifactsGast: Andrej Karpathy · Moderation: Lex FridmanOn Lex Fridman's podcast, Andrej Karpathy refuses the brain analogy, walks the Fermi paradox through Nick Lane's chemistry, and treats the Transformer as a general-purpose differentiable computer.
2:10:08ENGato Is Only the BeginningGast: Oriol Vinyals · Moderation: Lex FridmanDeepMind's Oriol Vinyals talks with Lex Fridman about generalist agents, thrown-away weights, and whether human-level AGI arrives in his lifetime.
2:10:39ENDemis Hassabis: Solve Intelligence, Then Solve Everything ElseGast: Demis Hassabis · Moderation: Lex FridmanThe DeepMind CEO tells Lex Fridman why the Turing Test is the wrong exam, how AlphaFold rewrote biology, and why the quiet radio sky suggests we are probably alone.
2:45:10ENA Teenager Learns to Drive in Twenty Hours. A Car Still Cannot.Gast: Yann Lecun · Moderation: Lex FridmanYann LeCun tells Lex Fridman why self-supervised world models are the missing dark matter of intelligence, and why machines are not even at the level of a house cat.
2:31:57ENJay McClelland on How Thought Emerges From Neural NetworksGast: Jay McClelland · Moderation: Lex FridmanThe Stanford cognitive scientist talks with Lex Fridman about connectionism, backpropagation, David Rumelhart, and why intuition discovers what logic later proves.
2:51:33ENThe Self Is a GPT Prompt: Wojciech Zaremba on Consciousness, Codex, and Fermi's SilenceGast: Wojciech Zaremba · Moderation: Lex FridmanOpenAI co-founder Wojciech Zaremba tells Lex Fridman he thinks we might be alone in the universe — and that GPT-3, Codex, and a one-handed robot already hint at how intelligence is built.
2:18:29ENYour Cortex Is 150,000 Brains Voting on a Coffee CupGast: Jeff Hawkins · Moderation: Lex FridmanJeff Hawkins tells Lex Fridman that intelligence is learning a model of the world, the neocortex is tens of thousands of independent maps that vote, and the fastest path to machine intelligence is reverse-engineering that sheet.
2:30:30ENThe Fallacy of the Successful First StepGast: Ishan Misra · Moderation: Lex FridmanBerkeley's Jitendra Malik explains why computer vision still looks easy, why fully autonomous driving is not near, and what children know that today's networks do not.
1:56:17ENIf You Reran Earth a Million Times, Would Anything Like Us Appear?Gast: Risto Miikkulainen · Moderation: Lex FridmanRisto Miikkulainen on neuroevolution, hyena raids, basil that never sleeps, and why variation-plus-selection still finds solutions backpropagation cannot see.
2:01:07ENMichael Littman isn’t waiting for a runaway god. He’s watching us.Gast: Michael Littman · Moderation: Lex FridmanThe Brown reinforcement-learning researcher tells Lex Fridman why accidental superintelligence feels like a 747 assembling itself — and why social media, rote language, and theory of mind worry him more.
2:10:06ENYou Might Have to Understand the World to Understand the Letter AGast: Dileep George · Moderation: Lex FridmanDileep George on recursive cortical networks, why a five-year-old can read any new CAPTCHA, and what the Wright brothers actually learned from birds.
1:41:37ENThe Fallacy of the Successful First Step: Jitendra Malik on Why Seeing Still Isn't SolvedGast: Jitendra Malik · Moderation: Lex FridmanBerkeley's Jitendra Malik tells Lex Fridman why computer vision keeps underestimating itself, why full self-driving still needs cognition, and why vision is the parent of language.
1:37:31ENThe Robot That Brought the Beer Was Being TeleoperatedGast: Sergey Levine · Moderation: Lex FridmanSergey Levine tells Lex Fridman why hardware is almost closed, why common sense has to be lived, and why offline reinforcement learning is the missing on-ramp from logs to robots that keep getting better.
2:00:32ENSlow Synapses Grow Fast Learners — Warmth Is the Harder ProblemGast: Matt Botvinick · Moderation: Lex FridmanDeepMind neuroscience director Matt Botvinick tells Lex Fridman how prefrontal cortex, meta-reinforcement learning, and dopamine research meet the human question of what a better life with AI would actually look like.
3:00:18ENOnly a Simulation Can Be ConsciousGast: Joscha Bach · Moderation: Lex FridmanJoscha Bach tells Lex Fridman why a neuron cannot feel anything, why existence is the default, and why this dying world is still the best level of the game.
1:37:28ENWe Are Still Massively Underestimating Deep LearningGast: Ilya Sutskever · Moderation: Lex FridmanIlya Sutskever tells Lex Fridman why 2012 was about conviction, why bigger models can get worse before they get better, and what he would do with an AGI.
1:48:01ENDavid Silver: AlphaGo Won by Taking Human Knowledge OutGast: David Silver · Moderation: Lex FridmanThe DeepMind researcher behind AlphaGo and AlphaZero tells Lex Fridman how an unclaimed million-dollar Go prize, a BBC Micro at age seven, and a honeymoon insight led to superhuman self-play.
1:12:48ENJohn Hopfield's Physics of Mind: Glitches Become FeaturesGast: John Hopfield · Moderation: Lex FridmanThe Princeton physicist walks Lex Fridman from a wobbly London bridge to Hopfield networks, consciousness-as-story, and why his famous model still does not explain learning.
1:44:55ENIf You Need 60,000 Digits, You Have Not Found IntelligenceGast: Vladimir Vapnik · Moderation: Lex FridmanVladimir Vapnik tells Lex Fridman that intelligence is the art of shrinking a sea of functions with a few good predicates — and that MNIST, solved with sixty examples per class, is the test.
49:53ENGilbert Strang still teaches with thick chalk and four subspacesGast: Gilbert Strang · Moderation: Lex FridmanThe MIT linear-algebra legend talks with Lex Fridman about OpenCourseWare, singular values, neural nets as a million folds, and why calculus hogged the undergraduate timetable.
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