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3:36:56ENPsychiatry Has Never Found Its PenicillinModeration: Lex FridmanHistorian Andrew Scull tells Lex Fridman why the field can ease symptoms, has never cured a major mental illness, and keeps paying for overconfidence with patients' lives.
2:03:23ENWe Have No King: How Viking Raiders Remade Medieval EuropeModeration: Lex FridmanHistorian Lars Brownworth walks Lex Fridman from Lindisfarne to Vinland, arguing that three centuries of raids were a lesson in speed, pragmatism, and creative destruction.
4:25:13ENThe Architecture Barely Changed. Data, Cost, and Open Weights Did.Moderation: Lex FridmanNathan Lambert and Sebastian Raschka walk Lex Fridman through a year in which training methods and datasets moved more than model design, and 2026 looks like a fight over inference cost, agents, and who owns truly open models.
3:52:17ENSome Infinities Are Larger Than OthersModeration: Lex FridmanJoel David Hamkins walks Lex Fridman from Hilbert's Hotel through Gödel, the continuum hypothesis, and a set-theoretic multiverse where truth is not the same as proof.
4:05:15ENThey could not agree whether Iran was building a bomb. They still wanted the same next move.Moderation: Lex FridmanAfter the Iran-Israel ceasefire, Scott Horton and Mark Dubowitz spend four hours on Lex Fridman arguing over enrichment math, a stolen archive, and whether bombing Fordo makes a weapon more likely or less.
3:15:17ENDemocrats still think politics runs on money. It runs on attention.Moderation: Lex FridmanEzra Klein and Derek Thompson tell Lex Fridman why the left keeps authorizing billions it cannot build, and why DOGE is a fight over control rather than efficiency.
5:06:18ENDeepSeek's $5 million training claim and the five-year bet on computeModeration: Lex FridmanDylan Patel and Nathan Lambert walk Lex Fridman through DeepSeek-V3 and R1, export controls, TSMC, megaclusters, and who actually makes money in the AI race.
57:45ENThe last thing a totalitarian state can take is love — a reread of Orwell’s 1984Moderation: Lex FridmanLex Fridman walks back through Oceania’s machinery of Newspeak, Doublethink, and Room 101, and argues that hate-fueled rebellion is not a way out.
6:17ENGSP would rather street-fight Ngannou than Bas RuttenModeration: Lex FridmanAfter their podcast, Georges St-Pierre walks Lex Fridman through a short clinic on surprise, dirty targets, knives, and why a UFC title is worthless against a blade.
1:02:32ENThe More Important the Issue, the Less Anyone Discusses ItModeration: Lex FridmanBernie Sanders tells Lex Fridman why drug lobbyists, campaign cash, and a healthcare system built for profit keep the biggest American problems off the table.
1:04:17ENTrump Tells Lex Fridman the Stick Usually WinsModeration: Lex FridmanDays before debating Kamala Harris, the former president talked winning, Ukraine, the 2020 election, and the border chart he still carries.
4:57:15ENThe Same Archive, Four Meanings: Finkelstein, Morris, Rabbani and Destiny Debate Israel and PalestineModeration: Lex FridmanA nearly five-hour Lex Fridman debate in which four opposed voices argue over 1948, October 7, Gaza, and whether any peace is still possible.
2:20:04ENShapiro vs Destiny: Two Questions That Never MeetModeration: Lex FridmanLex Fridman sits Ben Shapiro and Destiny down for a long-delayed debate on liberalism, Trump, Gaza, Ukraine, January 6, and whether history is allowed to go backward.
4:11:06ENThe climate problem is real. The 12-year asteroid story is not.Moderation: Lex FridmanBjørn Lomborg and Andrew Revkin tell Lex Fridman why vulnerability, cheaper tons of carbon, and energy innovation matter more than apocalyptic deadlines.
2:26:29ENYe said schools should teach only engineering. Then he spent an hour rewriting history.Moderation: Lex FridmanOn Lex Fridman’s podcast in October 2022, the artist formerly known as Kanye West talked design, family, and a theory about Jewish control that the host would not let stand.
4:05:22ENIf We Cannot Say What Life Is, We Cannot Recognize AliensModeration: Lex FridmanAstrobiologist Sara Walker and chemist Lee Cronin argue that the hunt for alien life is really a hunt for a physics of memory, objects, and time.
2:59:02ENWhen the Answers Are Already Known, Look Where Everyone Stopped LookingModeration: Lex FridmanGeorges St-Pierre, John Danaher, and Gordon Ryan sit with Lex Fridman to unpack success, confidence, training, and why the greatest of all time may not even be born yet.
2:58:05ENThe Declaration of 1776 and the Constitution of 1787 Pull in Opposite DirectionsModeration: Lex FridmanYaron Brook and Yoram Hazony spend three hours arguing whether a free society is built on the individual or on the sticky, hierarchical groups that individuals cannot live without.
2:54:52ENThe Marvelous Proof Still Lives in the MarginModeration: Lex FridmanLuís and João Batalha, the brothers behind Fermat's Library, talk with Lex Fridman about hidden backstories, a publishing system that buys its own work twice, and how to sit with a paper until it finally clicks.
4:25:18ENAn Anarchist and an Objectivist on a Desert IslandModeration: Lex FridmanLex Fridman sits Michael Malice and Yaron Brook down together for the first time to argue about Ayn Rand, human nature, Bitcoin, and whether liberty can exist without a state.
1:18:35ENAn AI That Walks Among Us May Have to Know DepressionModeration: Lex FridmanIn a January 2021 AMA, Lex Fridman answers listeners on suffering machines, immigration, aliens, career pivots, and why happiness is a signal rather than a goal.
2:02:45ENSteal the Code: You Get Zero Points for Making the Algorithm RunModeration: Lex FridmanCharles Isbell and Michael Littman tell Lex Fridman why machine learning is not just statistics, why struggle has to stay hopeful, and what a $6,600 online master's actually sells.
45:31ENYou Are Your Own Existence Proof: Karl Friston on Free Energy, Life, and Self-AwarenessModeration: Lex FridmanKarl Friston explains how the free energy principle reframes existence, life, planning, and self-awareness as inference problems.
17:19ENMoney Is a Game of Points: Vitalik Buterin on Coordination, Public Goods, and Quadratic FundingModeration: Lex FridmanVitalik Buterin explains money as a social point system, why value can survive without physical backing, and how quadratic funding tries to fix public-good underfunding.
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