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27:34ENJoseph Kim on Building AI Tools for Financial WorkGuest Joseph Kim · Host swyx, RichardOpenAI’s Joseph Kim discusses data, human review, taste and evaluations in building a financial-services product.
18:45ENJack Woodruff on AI and the Human Work of Stock PickingVinoo Ganesh, Jack Woodruff · KeplerThe former Candlestick Capital CIO discusses research, auditable data and how AI may reshape investment teams with Kepler CEO Vinoo Ganesh.
48:45ENPaul Copplestone on Databases for AI Builders and AgentsPaul Copplestone · SupabaseThe Supabase cofounder discusses the company’s growth, personal databases, agent-friendly tools and adapting to new kinds of builders.
51:35ENKarim Lakhani on Learning, Judgment and Work with AIGuest Karim R. Lakhani · Host Marina MogilkoThe Harvard Business School professor discusses how people can work with AI without surrendering their judgment or capacity to learn.
15:27ENRayan Krishnan on Model Evaluation Beyond the Model CardRayan Krishnan · Vals AIThe Vals AI cofounder explains why task-level accuracy, total cost and company-specific evaluations can change which model is the best fit.
19:06ENWojciech Pluta on Deciding What an AI Agent Should RememberWojciech Pluta · OracleOracle’s Wojciech Pluta explains memory promotion, a mortgage-agent demonstration, and the controls needed to carry useful information across sessions.
1:25:46ENAll-In on Anthropic’s IPO, AI Infrastructure and the Midterm ElectionsHost Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergThe hosts analyze Anthropic’s filing, debate the costs of an AI infrastructure boom, discuss Alphabet and offer competing midterm forecasts.
52:10ENJay Madheswaran on AI and the Economics of Plaintiff LawGuest Jay Madheswaran · Host Alex RampellEve’s CEO and a16z’s Alex Rampell discuss legal labor, case economics and the role of AI in plaintiff firms.
1:01:10ENRobert Caro on Power, Political Genius and a Life of ResearchGuest Robert Caro · Host Dwarkesh PatelThe biographer discusses Robert Moses, Lyndon Johnson and the discipline of investigating how power works.
49:29ENTheo on Agent Harnesses, Interfaces and Shifting AbstractionsTheo · T3 CodeThe T3 Code creator explains his model of harnesses and why he expects their differences to become less visible to users.
16:43ENIshween Kaur on Securing Agent Payments with x402Ishween Kaur · SoFiA testnet walkthrough of price changes, replay, premature delivery, lookalike sellers and prompt injection in agent payment flows.
2:42:18ENJoe Rogan and Legion of Skanks on Comedy, Animals and Life on the RoadGuest Big Jay Oakerson, Luis J. Gomez, Steve Rannazzisi · Host Joe RoganThe comedians trade stories about podcasting, wildlife, cars and the changing world of comedy.
52:54ENHard Fork on Anthropic’s IPO and the Week in AIGuest Erin Griffith, Mike Isaac, Jasmine Sun · Host Max ReadMax Read and guests discuss the filing, AI infrastructure, elections, cybersecurity and the changing tech workforce.
17:45ENKillian Carlsen-Phelan on Guiding and Verifying Coding AgentsKillian Carlsen-Phelan · SonarSonar demonstrates how project context and deterministic checks can be incorporated into a coding agent’s workflow.
23:33ENThe Fat Electrician Recounts the Life of Logan WestonGuest The Fat Electrician · Host Chris WilliamsonChris Williamson asks the military-history creator about the “Fighting Preacher,” whose service spanned World War II, Korea and the Vietnam era.
14:45ENMatthew Berman Examines Google’s Gemini 4 Carbon AnnouncementMatthew Berman · Forward FutureMatthew Berman reviews Google’s reported benchmark results, staged rollout and pricing for Gemini 4 Carbon, while noting he has not yet used the model.
38:07ENUsing Gitar to Verify Pull Requests Beyond the DiffTaylor Luttrell-Williams, Killian Carlsen-Phelan · SonarSonar’s Killian Carlsen-Phelan and Taylor Luttrell-Williams walk through ticket-transfer, pricing and CI-failure examples in a sample application.
41:49ENTheo Demonstrates T3 Code for Coordinating Coding AgentsTheo · t3.ggThe T3 Code creator walks through multiple agent providers, remote machines, thread organization and the tradeoffs of an open-source coding interface.
21:32ENShy Ruparel on AI agent reliability and recovery after failuresShy Ruparel · TemporalTemporal’s survey finds a gap between frequent agent use and dependable deployment. Ruparel demonstrates a synthetic payout workflow that resumes after workers stop.
50:51ENFred Graver on Using AI as a Writers’ Room, Not a GhostwriterGuest Fred Graver · Host Dan Shipper, Natalia QuinteroThe writer and producer explains how he develops ideas and uses AI feedback.
52:45ENSam Altman and John Collison on AI safety, compute and agent teamsGuest Sam Altman · Host John CollisonAltman discusses security, AI-assisted mathematics, infrastructure costs and personal agents, while Collison probes the limits of containment and the economics of compute.
2:58:50ENColum Tyrrell and Joe Rogan on Comedy, Ireland and the OutdoorsGuest Colum Tyrrell · Host Joe RoganThe comedians discuss Irish comedy, the pull of nature, media and the long process of developing a stand-up bit.
53:48ENMustafa Suleyman on AI Consciousness, Containment, and Human ControlGuest Mustafa Suleyman · Host Walter IsaacsonIn a conversation with Walter Isaacson, Microsoft AI’s CEO explains his disagreement over model welfare and the safeguards he believes increasingly capable systems need.
14:50ENCole Gannaway on code review, cross-repository risk and AI software factoriesCole Gannaway · QodoA one-line rename can pass local checks while affecting distant clients. Qodo’s Cole Gannaway explains how review context, shared rules and independent agents can expose those risks.
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